[HTML][HTML] Regulatory mechanism of icariin in cardiovascular and neurological diseases
Y Wang, C Shang, Y Zhang, L Xin, L Jiao… - Biomedicine & …, 2023 - Elsevier
Cardiovascular diseases (CVDs) and neurological diseases are widespread diseases with
substantial rates of morbidity and mortality around the world. For the past few years, the …
substantial rates of morbidity and mortality around the world. For the past few years, the …
Basic science of cardiac contractility modulation therapy: molecular and electrophysiological mechanisms
D Masarone, MM Kittleson, A D'Onofrio, L Falco… - Heart Rhythm, 2023 - Elsevier
In heart failure with reduced ejection fraction and heart failure with preserved ejection
fraction, profound cellular and molecular changes have recently been documented in the …
fraction, profound cellular and molecular changes have recently been documented in the …
PLAU is associated with cell migration and invasion and is regulated by transcription factor YY1 in cervical cancer
Y Gao, X Ma, H Lu, P Xu, C Xu - Oncology Reports, 2022 - spandidos-publications.com
Cervical cancer, one of the most common malignancies, has a poor survival rate. The
identification of more biomarkers for cervical cancer diagnosis and therapy is urgently …
identification of more biomarkers for cervical cancer diagnosis and therapy is urgently …
Transcription factor-mediated direct cellular reprogramming yields cell-type specific DNA methylation signature
Direct reprogramming, inducing the conversion of one type of somatic cell into another by
the forced expression of defined transcription factors, is a technology with anticipated …
the forced expression of defined transcription factors, is a technology with anticipated …
Upregulation of Phospholipase C Gene Expression Due to Norepinephrine-Induced Hypertrophic Response
PS Tappia, NS Dhalla - Cells, 2022 - mdpi.com
The activation of phospholipase C (PLC) is thought to have a key role in the cardiomyocyte
response to several different hypertrophic agents such as norepinephrine, angiotensin II and …
response to several different hypertrophic agents such as norepinephrine, angiotensin II and …
Modeling cardiomyocyte signaling and metabolism predicts genotype-to-phenotype mechanisms in hypertrophic cardiomyopathy
A Khalilimeybodi, JJ Saucerman… - Computers in Biology and …, 2024 - Elsevier
Familial hypertrophic cardiomyopathy (HCM) is a significant precursor of heart failure and
sudden cardiac death, primarily caused by mutations in sarcomeric and structural proteins …
sudden cardiac death, primarily caused by mutations in sarcomeric and structural proteins …
The benign nature and rare occurrence of cardiac myxoma as a possible consequence of the limited cardiac proliferative/regenerative potential: a systematic review
O Shafi, G Siddiqui, HA Jaffry - BMC cancer, 2023 - Springer
Abstract Background Cardiac Myxoma is a primary tumor of heart. Its origins, rarity of the
occurrence of primary cardiac tumors and how it may be related to limited cardiac …
occurrence of primary cardiac tumors and how it may be related to limited cardiac …
Vincristine attenuates isoprenaline-induced cardiac hypertrophy in male Wistar rats via suppression of ROS/NO/NF-қB signalling pathways
Vincristine (VCR), a vinca alkaloid with anti-tumor and anti-oxidant properties, is acclaimed
to possess cardioprotective action. However, the molecular mechanism underlying this …
to possess cardioprotective action. However, the molecular mechanism underlying this …
Transcriptional regulation of macrophages in heart failure
K Wang, X Sun, Y Sun, B Jiao, J Yao, Y Hu… - Frontiers in …, 2023 - frontiersin.org
Adverse cardiac remodeling after acute myocardial infarction is the most important
pathological mechanism of heart failure and remains a major problem in clinical practice …
pathological mechanism of heart failure and remains a major problem in clinical practice …
[PDF][PDF] A Comprehensive In Silico Study of the NDB-IL-24 Fusion Protein for Tumor Targeting: A Promising Anti-Cancer Therapeutic Candidate
HM Rehman, W Shoaib, MN Khan… - JOURNAL OF …, 2024 - researchgate.net
Background: Breast cancer remains a pervasive global health concern among women, with
conventional therapies such as chemotherapeutic agents, radiography, and surgery lacking …
conventional therapies such as chemotherapeutic agents, radiography, and surgery lacking …