Growth hormone supplementation may not improve live birth rate in poor responders

J Zhu, Y Wang, L Chen, P Liu, R Li… - Frontiers in endocrinology, 2020 - frontiersin.org
Backgrounds: Growth hormone (GH) was used for many years to increase ovarian response
in poor ovarian responders (PORs). Although meta-analysis suggested that GH therapy …

The effect of growth hormone adjuvant therapy on assisted reproductive technologies outcomes in patients with diminished ovarian reserve or poor ovarian response

S Dogan, OSY Cicek, M Demir, L Yalcinkaya… - Journal of gynecology …, 2021 - Elsevier
Low response of patients with diminished ovarian reserve to exogenous gonadotropins in
controlled ovarian stimulation (COS) protocols is one of the important problems of …

DHEA supplementation confers no additional benefit to that of growth hormone on pregnancy and live birth rates in IVF patients categorized as poor prognosis

KN Keane, PM Hinchliffe, PK Rowlands… - Frontiers in …, 2018 - frontiersin.org
Background In vitro fertilization (IVF) patients receive various adjuvant therapies to enhance
success rates, but the true benefit is actively debated. Growth hormone (GH) and …

Association between early embryo morphokinetics plus cumulus cell gene expression and assisted reproduction outcomes in polycystic ovary syndrome women

N Tabibnejad, MH Sheikhha, N Ghasemi… - Reproductive …, 2019 - Elsevier
Research question Can a combination of time-lapse morphokinetic parameters and cumulus
cell gene expression in polycystic ovary syndrome (PCOS) women be used to predict …

Human cumulus cell sensitivity to vitrification, an ultrastructural study

N Taghizabet, MA Khalili, F Anbari, A Agha-Rahimi… - Zygote, 2018 - cambridge.org
Cumulus cells (CCs) play an important role in the regulation of female gamete development,
meiotic maturation, oocyte–sperm interaction, capacitation and acrosome reaction …

Shifting paradigms in diminished ovarian reserve and advanced reproductive age in assisted reproduction: customization instead of conformity

BG Reed, SN Babayev… - Seminars in reproductive …, 2015 - thieme-connect.com
As women are increasingly delaying childbearing into their 30s and beyond, diminished
ovarian reserve (DOR) and advanced reproductive age (ARA) patients are bound to become …

Comparative efficacy of different growth hormone supplementation protocols in improving clinical outcomes in women with poor ovarian response undergoing …

Z Xu, W Tong, Z Yang, H Zhang, X Chen - Scientific Reports, 2024 - nature.com
Growth hormone (GH) has a long-standing history of use as an adjunctive therapy in the
treatment of poor ovarian response (POR), but the optimal dosage and timing remains …

Growth hormone for in vitro fertilisation (IVF)

A Sood, G Mohiyiddeen, G Ahmad… - Cochrane Database …, 2021 - cochranelibrary.com
Background In an effort to improve outcomes of in vitro fertilisation (IVF) cycles, the use of
growth hormone (GH) has been considered as adjuvant treatment in ovarian stimulation …

[HTML][HTML] Low dose growth hormone adjuvant treatment with ultra-long ovarian stimulation protocol in poor responders showed non-inferior pregnancy outcome …

YX Lee, MS Shen, CR Tzeng - Frontiers in Endocrinology, 2019 - frontiersin.org
Background: Growth hormone (GH) has long been used as adjuvant treatment in ovarian
stimulation for in vitro fertilization (IVF), especially in poor responder (PR) patients. However …

Growth hormone supplementation in the luteal phase before microdose GnRH agonist flare protocol for in vitro fertilization

C Dunne, K Seethram, J Roberts - Journal of obstetrics and gynaecology …, 2015 - Elsevier
Objective Growth hormone (GH) acts in both early and late follicular development to
stimulate the proliferation and differentiation of granulosa cells and to increase the …