[HTML][HTML] Livestock metabolomics and the livestock metabolome: A systematic review
Metabolomics uses advanced analytical chemistry techniques to comprehensively measure
large numbers of small molecule metabolites in cells, tissues and biofluids. The ability to …
large numbers of small molecule metabolites in cells, tissues and biofluids. The ability to …
The growing role of precision and personalized medicine for cancer treatment
Cancer is a devastating disease that takes the lives of hundreds of thousands of people
every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or …
every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or …
Cancer models in preclinical research: A chronicle review of advancement in effective cancer research
H Sajjad, S Imtiaz, T Noor, YH Siddiqui… - Animal Models and …, 2021 - Wiley Online Library
Cancer is a major stress for public well‐being and is the most dreadful disease. The models
used in the discovery of cancer treatment are continuously changing and extending toward …
used in the discovery of cancer treatment are continuously changing and extending toward …
Mass spectrometric based approaches in urine metabolomics and biomarker discovery
Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …
[HTML][HTML] Metabolomics for the masses: The future of metabolomics in a personalized world
Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
pathophysiology with patients and thus only describe a very limited metabolome of a patient …
[HTML][HTML] “Omics”-informed drug and biomarker discovery: opportunities, challenges and future perspectives
H Matthews, J Hanison, N Nirmalan - Proteomes, 2016 - mdpi.com
The pharmaceutical industry faces unsustainable program failure despite significant
increases in investment. Dwindling discovery pipelines, rapidly expanding R&D budgets …
increases in investment. Dwindling discovery pipelines, rapidly expanding R&D budgets …
[HTML][HTML] Standardizing the experimental conditions for using urine in NMR-based metabolomic studies with a particular focus on diagnostic studies: a review
The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …
prognostic information. Among the biofluids most commonly analyzed in metabolomic …
[HTML][HTML] Advantages and pitfalls of mass spectrometry based metabolome profiling in systems biology
I Aretz, D Meierhofer - International journal of molecular sciences, 2016 - mdpi.com
Mass spectrometry-based metabolome profiling became the method of choice in systems
biology approaches and aims to enhance biological understanding of complex biological …
biology approaches and aims to enhance biological understanding of complex biological …
Overview of systems biology and omics technologies
B Karahalil - Current medicinal chemistry, 2016 - ingentaconnect.com
Traditional technologies using reductionist approach are relatively insufficient to solve
problems in a biological system. Rather than a reductionist approach, systems biology uses …
problems in a biological system. Rather than a reductionist approach, systems biology uses …
Metabolomics in the study of retinal health and disease
I Laíns, M Gantner, S Murinello, JA Lasky-Su… - Progress in retinal and …, 2019 - Elsevier
Metabolomics is the qualitative and quantitative assessment of the metabolites (small
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …