Metabolomics uses advanced analytical chemistry techniques to comprehensively measure
large numbers of small molecule metabolites in cells, tissues and biofluids. The ability to …

Cancer is a devastating disease that takes the lives of hundreds of thousands of people
every year. Due to disease heterogeneity, standard treatments, such as chemotherapy or …

Cancer is a major stress for public well‐being and is the most dreadful disease. The models
used in the discovery of cancer treatment are continuously changing and extending toward …

Urine metabolomics has recently emerged as a prominent field for the discovery of non‐
invasive biomarkers that can detect subtle metabolic discrepancies in response to a specific …

Current clinical practices focus on a small number of biochemical directly related to the
pathophysiology with patients and thus only describe a very limited metabolome of a patient …

The pharmaceutical industry faces unsustainable program failure despite significant
increases in investment. Dwindling discovery pipelines, rapidly expanding R&D budgets …

The metabolic composition of human biofluids can provide important diagnostic and
prognostic information. Among the biofluids most commonly analyzed in metabolomic …

Mass spectrometry-based metabolome profiling became the method of choice in systems
biology approaches and aims to enhance biological understanding of complex biological …

Traditional technologies using reductionist approach are relatively insufficient to solve
problems in a biological system. Rather than a reductionist approach, systems biology uses …

Metabolomics is the qualitative and quantitative assessment of the metabolites (small
molecules< 1.5 kDa) in body fluids. The metabolites are the downstream of the genetic …