We reported recently that a pituitary‐specific transcription factor PROP1 is present in SOX2‐
positive cells and disappears at the early stage of the transition from progenitor cell to …

Abstract Context: The Lhx3 LIM-homeodomain transcription factor gene is required for
development of the pituitary and motoneurons in mice. Human LHX3 gene mutations have …

Mutations in PROP1, the most common known cause of combined pituitary hormone
deficiency in humans, can result in the progressive loss of all hormones of the pituitary …

The pituitary gland is a complex organ secreting six hormones from five different cell types. It
is the end product of a carefully orchestrated pattern of expression of signalling molecules …

The embryonic development of the pituitary gland involves a complex and highly spatio-
temporally regulated network of integrating signalling molecules and transcription factors …

Magnetic resonance imaging (MRI) is the radiological examination method of choice for
evaluating hypothalamo‐pituitary‐related endocrine disease and is considered essential in …

The intermediate and anterior lobes of the pituitary gland are derived from an invagination of
oral ectoderm that forms Rathke's pouch. During gestation proliferating cells are enriched …

Bone morphogenetic protein (Bmp) signaling is critical for the development and patterning of
the mouse pituitary from the initial induction of Rathke's pouch to cell specification in the …

Prophet of PIT1 (PROP1) is a pituitary-specific factor and responsive gene for the combined
pituitary hormone deficiency in Ames dwarf mice and human patients. Our …

The anterior pituitary is made up of a number of cell types that are essential for such
physiological processes as growth, development, homeostasis, metabolism, and …