p63-related signaling at a glance

ML Fisher, S Balinth, AA Mills - Journal of cell science, 2020 - journals.biologists.com
ABSTRACT p63 (also known as TP63) is a transcription factor of the p53 family, along with
p73. Multiple isoforms of p63 have been discovered and these have diverse functions …

Downregulation of microRNA-146a in diabetes, obesity and hypertension may contribute to severe COVID-19

J Roganović - Medical Hypotheses, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is able to
produce an excessive host immune reaction and may leads to severe disease-a life …

Pharmacological Effects of Centella asiatica on Skin Diseases: Evidence and Possible Mechanisms

KS Park - Evidence‐Based Complementary and Alternative …, 2021 - Wiley Online Library
The medicinal herb Centella asiatica (L.) Urban known as gotu kola has been reported to
exhibit a wide range of pharmacological activities. In particular, a significant body of …

[HTML][HTML] Ameliorative Effects of Peptides Derived from Oyster (Crassostrea gigas) on Immunomodulatory Function and Gut Microbiota Structure in Cyclophosphamide …

XW Xiang, HZ Zheng, R Wang, H Chen, JX Xiao… - Marine Drugs, 2021 - mdpi.com
The intestinal flora is recognized as a significant contributor to the immune system. In this
research, the protective effects of oyster peptides on immune regulation and intestinal …

[HTML][HTML] α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect

H Liu, X Zhang, P Shi, J Yuan, Q Jia, C Pi… - Journal of …, 2023 - Springer
Depression is a common mental illness, which is related to monoamine neurotransmitters
and the dysfunction of the cholinergic, immune, glutamatergic, and neuroendocrine systems …

[PDF][PDF] SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium

AZ Eriksen, R Møller, B Makovoz, SA Uhl… - Cell stem cell, 2021 - cell.com
The SARS-CoV-2 pandemic has caused unparalleled disruption of global behavior and
significant loss of life. To minimize SARS-CoV-2 spread, understanding the mechanisms of …

[HTML][HTML] HIF-1α in osteoarthritis: from pathogenesis to therapeutic implications

CY Zeng, XF Wang, FZ Hua - Frontiers in Pharmacology, 2022 - frontiersin.org
Osteoarthritis is a common age-related joint degenerative disease. Pain, swelling, brief
morning stiffness, and functional limitations are its main characteristics. There are still no …

[HTML][HTML] Epigenetic programing of cancer stemness by transcription factors-non-coding RNAs interactions

RKME Alsayed, KSAM Sheikhan, MA Alam… - Seminars in Cancer …, 2023 - Elsevier
Cancer 'stemness' is fundamental to cancer existence. It defines the ability of cancer cells to
indefinitely perpetuate as well as differentiate. Cancer stem cell populations within a …

The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view

EHM Hassanein, WR Mohamed, OS Ahmed… - Life Sciences, 2022 - Elsevier
Kidney diseases are major health problem and understanding the underlined mechanisms
that lead to kidney diseases are critical research points with a marked potential impact on …

[HTML][HTML] Role and mechanisms of the NF-ĸB signaling pathway in various developmental processes

P Liu, Y Li, W Wang, Y Bai, H Jia, Z Yuan… - Biomedicine & …, 2022 - Elsevier
Since the discovery of the nuclear factor kappa B (NF-ĸB) transcription factor 36 years ago,
many studies have linked the NF-ĸB signaling pathway to pathological and physiological …