The importance of phosphate homeostasis in chronic kidney disease (CKD) has been
recognized for decades, but novel insights—which are frequently relevant to everyday …

Traditional dietary recommendations to renal patients limited the intake of fruits and
vegetables because of their high potassium content. However, this paradigm is rapidly …

Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical
Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of …

Masafumi Fukagawa, 1 Keitaro Yokoyama, 1 Fumihiko Koiwa, 1 Masatomo Taniguchi, 1
Tetsuo Shoji, 1 Junichiro James Kazama, 1 Hirotaka Komaba, 1 Ryoichi Ando, 1 Takatoshi …

In mammals, phosphate balance is maintained by influx and efflux via the intestines,
kidneys, bone, and soft tissue, which involves multiple sodium/phosphate (Na+/Pi) …

Results FGF23 correlated directly with IL-6 (r= 0.4), CRP (r= 0.2), TNF-α (r= 0.4), and
fibrinogen (r= 0.3; P< 0.001 for each). In univariate and multivariable-adjusted linear …

Disturbances in phosphate homeostasis are common in patients with chronic kidney
disease. As kidney function declines, circulating concentrations of phosphate and the …

Backgound: The term 'joint modelling'is used in the statistical literature to refer to methods for
simultaneously analysing longitudinal measurement outcomes, also called repeated …

Treatment of chronic kidney disease (CKD) can slow its progression to end-stage renal
disease (ESRD). However, the therapies remain limited. Blood pressure control using …

Background Guidelines recommend reducing elevated serum phosphate in patients with
CKD. Tenapanor, a minimally absorbed inhibitor of gastrointestinal sodium/hydrogen …