MicroRNA biomarkers for infectious diseases: from basic research to biosensing

L Tribolet, E Kerr, C Cowled, AGD Bean… - Frontiers in …, 2020 - frontiersin.org
In the pursuit of improved diagnostic tests for infectious diseases, several classes of
molecules have been scrutinized as prospective biomarkers. Small (18–22 nucleotide), non …

Infection biomarkers based on metabolomics

R Araújo, LFN Bento, TAH Fonseca, CP Von Rekowski… - Metabolites, 2022 - mdpi.com
Current infection biomarkers are highly limited since they have low capability to predict
infection in the presence of confounding processes such as in non-infectious inflammatory …

ITIH4, as an inflammation biomarker, mainly increases in bacterial bloodstream infection

Y Ma, R Li, J Wang, W Jiang, X Yuan, J Cui, C Wang - Cytokine, 2021 - Elsevier
Bloodstream infection (BSI) is usually accompanied with the changes of varieties of
inflammation proteins. In our previous study, we identified that inter-α-trypsin inhibitor heavy …

Combined procalcitonin and hemogram parameters contribute to early differential diagnosis of Gram‐negative/Gram‐positive bloodstream infections

Q Gao, Z Li, X Mo, Y Wu, H Zhou… - Journal of Clinical …, 2021 - Wiley Online Library
Background Hemogram parameters and procalcitonin (PCT) play auxiliary roles in the
diagnosis and outcome of sepsis. However, it is not clear whether these indicators can …

[HTML][HTML] Biomarkers in sepsis-looking for the Holy Grail or chasing a mirage!

N Ahuja, A Mishra, R Gupta, S Ray - World Journal of Critical Care …, 2023 - ncbi.nlm.nih.gov
Sepsis is defined as a life-threatening organ dysfunction caused by the dysregulated host
response to infection. It is a complex syndrome and is characterized by physiologic …

Evaluation of the relationship between procalcitonin level and the causative pathogen in intensive care patients with sepsis

M Bilgin, R Aci, A Keskin, EM Yilmaz, E Polat - Future Microbiology, 2023 - Taylor & Francis
Aim: This study was designed to investigate how procalcitonin (PCT) levels are affected by
different pathogens in patients with sepsis. Materials & methods: A total of 110 Gram-positive …

Diagnostic accuracy of interleukin-6 in multiple diseases: An umbrella review of meta-analyses

Z Han, J Li, X Yi, T Zhang, D Liao, J You, J Ai - Heliyon, 2024 - cell.com
Objective This review aims to conduct a comprehensive study of the diagnostic accuracy of
interleukin-6 (IL-6) for multiple diseases by utilizing existing systematic reviews and meta …

IL-6 and IL-10 closely correlate with bacterial bloodstream infection

J Guan, Z Wang, X Liu, Y Jiang, Q Gao, Q Wu… - Iranian Journal of …, 2020 - iji.sums.ac.ir
Background: Given the high mortality of bacterial bloodstream infections (BSI), blood culture
results do not meet clinical needs timely due to being time-consuming and having low …

Diagnostic value of serum CRP, PCT and IL-6 in children with nephrotic syndrome complicated by infection: a single center retrospective study

W Jia, W Dou, H Zeng, Q Wang, P Shi, J Liu, Z Liu… - Pediatric …, 2024 - nature.com
Objective The purpose was to look into the diagnostic value of serum CRP, PCT and IL-6 in
children with nephrotic syndrome co-infection. Methods One hundred and forty-nine children …

[HTML][HTML] Precisión diagnóstica de la procalcitonina para la bacteriemia en el servicio de urgencias: una revisión sistemática

A Julián-Jiménez, DE García… - Revista Española de …, 2024 - ncbi.nlm.nih.gov
Método Se realiza una revisión sistemática siguiendo la normativa PRISMA en las bases de
datos de PubMed, Web of Sciencie, EMBASE, Lilacs, Cochrane, Epistemonikos, Tripdata …