SIRT1: a potential therapeutic target in autoimmune diseases

P Shen, X Deng, Z Chen, X Ba, K Qin, Y Huang… - Frontiers in …, 2021 - frontiersin.org
The morbidity and mortality of autoimmune diseases (Ads) have been increasing worldwide,
and the identification of novel therapeutic strategies for prevention and treatment is urgently …

Clinically relevant circulating protein biomarkers for type 1 diabetes: evidence from a two-sample Mendelian randomization study

N Yazdanpanah, M Yazdanpanah, Y Wang… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE To identify circulating proteins influencing type 1 diabetes susceptibility using
Mendelian randomization (MR). RESEARCH DESIGN AND METHODS We used a large …

[HTML][HTML] Targeting IL-12 family cytokines: A potential strategy for type 1 and type 2 diabetes mellitus

J Luo, T Ning, X Li, T Jiang, S Tan, D Ma - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Diabetes is a common metabolic disease characterized by an imbalance in blood glucose
levels. The pathogenesis of diabetes involves the essential role of cytokines, particularly the …

[HTML][HTML] Evaluation of Rosuvastatin Therapy on SIRT1 Gene Expression in Patients with Multiple Sclerosis: An Uncontrolled Clinical Trial

S Batoee, M Etminaniesfahani, M Mazdeh… - Current Therapeutic …, 2023 - Elsevier
Background Multiple sclerosis (MS) is a chronic autoimmune disease. Current medications
have some limitations such as low efficacy and high side effects. In recent years, statins …

Advances in Molecular Biomarkers in Cardiology

P Scicchitano, M Cameli - Biomolecules, 2022 - mdpi.com
Cardiovascular diseases (CVD) represent the leading cause of death in the world despite
innovations in therapies and advances in the general management of patients [1]. Early …

[PDF][PDF] Comprehensive assessment of Cardiovascular-Kidney-Metabolic (CKM) syndrome: Novel tools for assessment of cardiovascular risk and kidney outcomes in …

K Batko, A Sączek, M Banaszkiewicz… - Polish Heart …, 2024 - journals.viamedica.pl
ABSTRACT Background: The cardiovascular (CV)-kidney-metabolic (CKM) syndrome, a
newly-defined entity, offers a framework for assessing CV risk. Emerging evidence suggests …

Is thyroid autoimmunity associated with subclinical atherosclerosis in young women with type 1 diabetes mellitus?

MM Łukawska-Tatarczuk, J Zieliński… - Endokrynologia …, 2022 - journals.viamedica.pl
Introduction: It has been hypothesized that autoimmunity may contribute to cardiovascular
complications and may be an important trigger for processes leading to atherosclerosis …

Identification of key genes and biological pathways in chronic obstructive pulmonary disease using bioinformatics and next generation sequencing data analysis

BM Vastrad, CM Vastrad - bioRxiv, 2024 - biorxiv.org
Identification of accurate biomarkers is still particularly urgent for improving the poor survival
of chronic obstructive pulmonary disease (COPD) patients. In this investigation, we aimed to …

Association of antithyroid peroxidase antibodies with cardiac function in euthyroid women with type 1 diabetes mellitus—assessment with two-dimensional speckle …

MM Łukawska-Tatarczuk, A Pawlak… - Endokrynologia …, 2022 - journals.viamedica.pl
Introduction: The presence of diabetes is associated with loss of cardioprotecti on in
premenopausal women; however, the mechanisms involved remain unknown. Autoimmune …

The effect of visfatin genotype on insulin pump therapy on quality of life in patients with type I diabetes

L Jianjun, L Xiaona, L Hong - Cellular and Molecular Biology, 2021 - cellmolbiol.org
Diabetes is associated with an increase in other chronic diseases and an increase in
mortality. The individual differences influence the treatment of this disease in …