Human abdominal aortic aneurysm (AAA) pathophysiology is not yet completely understood.
In conductance arteries, the insoluble extracellular matrix, synthesized by vascular smooth …

Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …

Rationale: Pulmonary hypertension (PH) is a life-threatening cardiopulmonary disorder in
which inflammation and immunity have emerged as critical early pathogenic elements …

Abdominal aortic aneurysm (AAA), a deadly vascular disease in human, is a chronic
degenerative process of the abdominal aorta. In this process, inflammatory responses and …

Abdominal aortic aneurism (AAA) is a complex immunological disease with a strong genetic
component, and one of the ten leading causes of death of individuals 55–74 years old …

The complement alternative pathway is a powerful arm of the innate immune system that
enhances diverse inflammatory responses in the human host. Key to the effects of the …

Kawasaki disease (KD) is a pediatric vasculitis syndrome that is often involves coronary
artery lesions (eg, coronary artery aneurysms). Although its causal factors and entire …

Background Abdominal aortic aneurysm (AAA) is a potentially life‐threatening disease that
is common in older individuals. Currently, therapeutic options are limited to surgical …

Background Abdominal aortic aneurysm (AAA), a degenerative vascular pathology
characterized by permanent dilation of the aorta, is considered a chronic inflammatory …

Abstract Pulmonary (arterial) hypertension (PH/PAH) is a life-threatening cardiopulmonary
disorder. Experimental evidence suggests involvement of inflammatory and autoimmune …