Antibiotics are regarded as a miracle in the medical field as it prevents disease caused by
pathogenic bacteria. Since the discovery of penicillin, antibiotics have become the …

The growing prevalence of antimicrobial resistance (AMR) has brought with it a continual
increase in the numbers of deaths from multidrug-resistant (MDR) infections. Since the …

Antisense peptide nucleic acids (PNAs) that target mRNAs of essential bacterial genes
exhibit specific bactericidal effects in several microbial species, but our mechanistic …

Antimicrobial peptides (AMPs) are short oligopeptides that can penetrate the bacterial inner
and outer membranes. Together with cell-penetrating peptides (CPPs), they are called …

Precision antisense antibacterial agents may be developed into novel antibiotics in the fight
against multidrug-resistant Gram-negative bacteria. In this study, a series of …

Biofilm‐associated infections are one of the most challenging healthcare threats for humans,
accounting for 80% of bacterial infections, leading to persistent and chronic infections. The …

Antimicrobial agents targeting peptidoglycan have shown successful results in eliminating
bacteria with high selective toxicity. Bacteriophage encoded endolysin as an alternative …

Peptide nucleic acid (PNA) is a nucleic acid mimic with high specificity and binding affinity to
natural DNA or RNA, as well as resistance to enzymatic degradation. PNA sequences can …

While the rise of superbugs and new resistance mechanisms continues decreasing the
effectiveness of classical antibiotics, antimicrobial peptides (AMPs) are emerging as a new …

The chemophysical properties of a peptide isolated from Olivancillaria hiatula were
combined with computational tools to design new antimicrobial peptides (AMPs). The in …