Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Automatic segmentation of subcortical structures in human brain MR images is an important
but difficult task due to poor and variable intensity contrast. Clear, well-defined intensity …

Scientific evidence based on neuroimaging approaches over the last decade has
demonstrated the efficacy of physical activity improving cognitive health across the human …

In this Seminar we discuss developments from the past 5 years in the diagnosis,
neurobiology, and treatment of major depressive disorder. For diagnosis, psychiatric and …

Engagement in regular bouts of exercise confers numerous positive effects on brain health
across the lifespan. Acute bouts of exercise transiently improve cognitive function, while long …

The growth factor brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-
related kinase receptor type B (TRKB) are actively produced and trafficked in multiple …

In general, it is well recognized that both acute physical exercises and regular physical
training influence brain plasticity and cognitive functions positively. However, growing …

We have recently shown that a single bout of acute cardiovascular exercise improves motor
skill learning through an optimization of long-term motor memory. Here we expand this …

Research has shown the human brain is organized into separable functional networks
during rest and varied states of cognition, and that aging is associated with specific network …

Neurotrophins, such as brain-derived neurotrophic factor (BDNF), are prominent regulators
of neuronal survival, growth and differentiation during development. While trophic factors are …