Pancreatic ductal adenocarcinoma (PDAC) is one of the lethal malignancies with the lowest
median and overall survival rate among all human malignancies. The major problems with …

The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

Background Pancreatic cancer is one of the most lethal malignancies and has an extremely
poor diagnosis and prognosis. The development of resistance to gemcitabine is still a major …

In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

Pancreatic cancer is one of the most common causes of cancer death in the world due to the
lack of early symptoms, metastasis occurrence and chemoresistance. Therefore, early …

Abstract Development of resistance to chemotherapeutic drugs is a major challenge in the
care of patients with pancreatic ductal adenocarcinoma (PDAC). Acquired resistance to …

Background Previous studies identified microRNAs (miRNAs) and messenger RNAs with
significantly different expression between normal pancreas and pancreatic cancer (PDAC) …

Numerous studies have shown that non-coding RNAs play crucial roles in the development
and progression of various tumor cells. Plasmacytoma variant translocation 1 (PVT1) mainly …

Background: We previously conducted gene expression microarray analyses to identify
novel indicators for colorectal cancer (CRC) metastasis and prognosis from which we …

Chemoresistance including intrinsic and acquired anticancer drug resistance continues to
be a primary hindrance towards curative cancer treatment. Therefore, deciphering the …