Rotational thromboelastometry (ROTEM) is a point-of-care viscoelastic method and enables
to assess viscoelastic profiles of whole blood in various clinical settings. ROTEM-guided …

Hemorrhage is the leading cause of preventable death in combat trauma and the secondary
cause of death in civilian trauma. A significant number of deaths due to hemorrhage occur …

Guidelines Management of severe peri-operative bleeding: Guidelines from the European
Society of Anaesthesiology and Intensive Care

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Importance Critical bleeding is associated with a high mortality rate in patients with trauma.
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …

Importance Optimal transfusion strategies in traumatic hemorrhage are unknown. Reports
suggest a beneficial effect of 4-factor prothrombin complex concentrate (4F-PCC) on blood …

Background Major haemorrhage is a clinical emergency that results in morbidity and
mortality: practice guidance is important to reduce these risks. Delayed recognition of …

ORCA – Online Research @ Cardiff Page 1 ORCA – Online Research @ Cardiff This is an
Open Access document downloaded from ORCA, Cardiff University's institutional repository:https://orca.cardiff.ac.uk/id/eprint/115006 …

Purpose To develop evidence-based clinical practice recommendations regarding
transfusion practices and transfusion in bleeding critically ill adults. Methods A taskforce …

Background Severe trauma represents a major global public health burden and the
management of post-traumatic bleeding continues to challenge healthcare systems around …