Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Biological functions of chromobox (CBX) proteins in stem cell self-renewal, lineage-commitment, cancer and development

AJ van Wijnen, L Bagheri, AA Badreldin, AN Larson… - Bone, 2021 - Elsevier
Epigenetic regulatory proteins support mammalian development, cancer, aging and tissue
repair by controlling many cellular processes including stem cell self-renewal, lineage …

Codelivery of STAT3 siRNA and BV6 by carboxymethyl dextran trimethyl chitosan nanoparticles suppresses cancer cell progression

A Nikkhoo, N Rostami, S Farhadi, M Esmaily… - International journal of …, 2020 - Elsevier
High expression of inhibitor of apoptosis (IAP) molecules in cancer cells promotes cancer
cell chemoresistance. Use of BV6, a well-known IAP inhibitor, along with inhibition of signal …

Non-coding RNA profile in lung cancer

S Ghafouri-Fard, H Shoorei, W Branicki… - … and molecular pathology, 2020 - Elsevier
Lung cancer is the most frequently diagnosed malignancy and the leading source of cancer-
associated mortality. This kind of cancer has heterogeneous nature and is divided into two …

[HTML][HTML] CBX4 deletion promotes tumorigenesis under KrasG12D background by inducing genomic instability

F Chen, W Hou, X Yu, J Wu, Z Li, J Xu, Z Deng… - … and Targeted Therapy, 2023 - nature.com
Abstract Chromobox protein homolog 4 (CBX4) is a component of the Polycomb group
(PcG) multiprotein Polycomb repressive complexes 1 (PRC1), which is participated in …

Current landscape of epigenetics in lung cancer: focus on the mechanism and application

YX Shi, DQ Sheng, L Cheng, XY Song - Journal of oncology, 2019 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related mortality worldwide. Tumorigenesis
involves a multistep process resulting from the interactions of genetic, epigenetic, and …

[HTML][HTML] Radon biomonitoring and microRNA in lung cancer

R Bersimbaev, A Pulliero, O Bulgakova… - International journal of …, 2020 - mdpi.com
Radon is the number one cause of lung cancer in non-smokers. microRNA expression in
human bronchial epithelium cells is altered by radon, with particular reference to …

miR-19 family: A promising biomarker and therapeutic target in heart, vessels and neurons

X Li, C Teng, J Ma, N Fu, L Wang, J Wen, TY Wang - Life sciences, 2019 - Elsevier
The miR-19 family, including miR-19a, miR-19b-1 and miR-19b-2, arises from two different
paralogous clusters miR-17-92 and miR-106a-363. Although it is identified as oncogenic …

[HTML][HTML] TAp63α is involved in tobacco smoke-induced lung cancer EMT and the anti-cancer activity of curcumin via miR-19 transcriptional suppression

C Xie, J Zhu, X Yang, C Huang, L Zhou… - Frontiers in cell and …, 2021 - frontiersin.org
As a key risk factor for lung cancer, tobacco smoke (TS) influences several cellular
processes, including epithelial-mesenchymal transition (EMT). TAp63α is a crucial …

MiR-34c acts as a tumor suppressor in non-small cell lung cancer by inducing endoplasmic reticulum stress through targeting HMGB1

L Tu, X Long, W Song, Z Lv, H Zeng, T Wang… - OncoTargets and …, 2019 - Taylor & Francis
Objective To investigate the role of miR-34c in lung cancer. Methods The levels of microRNA-
34c (miR-34c) expression in non-small cell lung cancer (NSCLC) tissue and cell lines were …