Clinical phenotypes of heart failure with preserved ejection fraction to select preclinical animal models

WB van Ham, EL Kessler, MIFJ Oerlemans… - Basic to Translational …, 2022 - jacc.org
At least one-half of the growing heart failure population consists of heart failure with
preserved ejection fraction (HFpEF). The limited therapeutic options, the complexity of the …

Interleukin-22: a potential therapeutic target in atherosclerosis

JW Luo, Y Hu, J Liu, H Yang, P Huang - Molecular medicine, 2021 - Springer
Background Atherosclerosis is recognized as a chronic immuno-inflammatory disease that is
characterized by the accumulation of immune cells and lipids in the vascular wall. In this …

Solvation dynamics of tetracyclic irbesartan in water and dichloromethane: Insights from local energy decomposition and ab initio molecular dynamics simulations …

ES Aazam, R Thomas - Journal of Molecular Liquids, 2022 - Elsevier
Solvation energy changes Gibb's energy when an ion or molecule is transferred from a
vacuum to a solvent. Solvation is the attraction and association of molecules of a solvent …

Interleukin-22 exacerbates angiotensin II-induced hypertensive renal injury

W Wang, Y Lu, X Hu, H Li, X Li, C Xiao, T Meng… - International …, 2022 - Elsevier
Hypertensive renal injury (HRI) is a main cause of end-stage renal diseases, and CD4+ T
cells and the secreted inflammatory cytokines contribute to the progress of HRI. However …

Cytokines and chemokines multiplex analysis in patients with low disease activity rheumatoid arthritis

M Skrzypkowska, M Stasiak, J Sakowska… - Rheumatology …, 2022 - Springer
Rheumatoid arthritis is a severe chronic autoimmune disorder that results from pathological
activation of immune cells and altered cytokine/chemokine network. The aim of our study …

Current perspectives and trends of the research on hypertensive nephropathy: a bibliometric analysis from 2000 to 2023

L Wang, J Wang, Y Zhang, H Zhang - Renal Failure, 2024 - Taylor & Francis
Hypertensive nephropathy continues to be a major cause of end-stage renal disease and
poses a significant global health burden. Despite the staggering development of research in …

Catalpol Alleviates Ang II-Induced Renal Injury Through NF‐κB Pathway and TGF-β1/Smads Pathway

C Cong, X Yuan, Y Hu, W Chen… - Journal of …, 2022 - journals.lww.com
Catalpol is an iridoid glycoside obtained from Rehmannia glutinosa, which in previous
studies showed various pharmacological properties, including anti-inflammatory …

[HTML][HTML] Huangkui capsule in combination with leflunomide improves immunoglobulin A nephropathy by inhibiting the TGF-β1/Smad3 signaling pathway

S Pei, Y Li - Clinics, 2021 - SciELO Brasil
OBJECTIVES: To investigate the efficacy and potential molecular mechanism of Huangkui
capsule in combination with leflunomide (HKL) for the treatment of immunoglobulin A …

Mining Anti-Inflammation Molecules From Nippostrongylus brasiliensis-Derived Products Through the Metabolomics Approach

Y Chen, M Zhang, X Ding, Y Yang, Y Chen… - Frontiers in Cellular …, 2021 - frontiersin.org
Hookworm is one type of soil-transmitted helminth, which could exert an anti-inflammatory
effect in human or animal host, which provides a beneficial possibility for the discovery of …

[PDF][PDF] 厄贝沙坦片联合益生菌对高血压伴肥胖患者的疗效及对肠道菌群的调控作用

李守刚, 于丹丹, 赵璐 - 中国微生态学杂志, 2023 - cjm.dmu.edu.cn
目的探讨厄贝沙坦片联合益生菌对高血压伴肥胖患者的疗效及对肠道菌群的调控作用.
方法选取2021 年10 月—2022 年10 月本院400 例高血压伴肥胖患者. 随机法分组: 对照组(200 …