The T-box family of transcription factors exhibits widespread involvement throughout
development in all metazoans. T-box proteins are characterized by a DNA-binding motif …

Myelination of axons provides the structural basis for rapid saltatory impulse propagation
along vertebrate fiber tracts, a well-established neurophysiological concept. However …

Stem-cell differentiation to desired lineages requires navigating alternating developmental
paths that often lead to unwanted cell types. Hence, comprehensive developmental …

Visceral organs, such as the lungs, stomach and liver, are derived from the fetal foregut
through a series of inductive interactions between the definitive endoderm (DE) and the …

Current protocols for the differentiation of human pluripotent stem cells (hPSCs) into
chondrocytes do not allow for the expansion of intermediate progenitors so as to …

Limb position along the body is highly consistent within one species but very variable
among vertebrates. Despite major advances in our understanding of limb patterning in three …

Background Kiwi, comprising five species from the genus Apteryx, are endangered, ground-
dwelling bird species endemic to New Zealand. They are the smallest and only nocturnal …

Mesoderm is the developmental precursor to myriad human tissues including bone, heart,
and skeletal muscle. Unravelling the molecular events through which these lineages …

We present a draft genome of the little bush moa (Anomalopteryx didiformis)—one of
approximately nine species of extinct flightless birds from Aotearoa, New Zealand—using …

Newly discovered pelvic and reproductive structures within placoderms, representing some
of the most crownward members of the gnathostome stem group and the most basal jawed …