[HTML][HTML] Ginsenosides in Panax genus and their biosynthesis

M Hou, R Wang, S Zhao, Z Wang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Ginsenosides are a series of glycosylated triterpenoids which belong to protopanaxadiol
(PPD)-, protopanaxatriol (PPT)-, ocotillol (OCT)-and oleanane (OA)-type saponins known as …

Why traditional herbal medicine promotes wound healing: Research from immune response, wound microbiome to controlled delivery

Z Xu, M Dong, S Yin, J Dong, M Zhang, R Tian… - Advanced Drug Delivery …, 2023 - Elsevier
Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

Role of the PI3K/AKT (mTOR and GSK3β) signalling pathway and photobiomodulation in diabetic wound healing

SW Jere, NN Houreld, H Abrahamse - Cytokine & Growth Factor Reviews, 2019 - Elsevier
Activated phosphatidylinositol 3 kinase/Protein kinase B (PI3K/AKT) signalling with
increased or reduced mTOR and GSK3β activity influences the wound repair process …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

Encapsulation of green tea polyphenol nanospheres in PVA/alginate hydrogel for promoting wound healing of diabetic rats by regulating PI3K/AKT pathway

G Chen, L He, P Zhang, J Zhang, X Mei, D Wang… - Materials Science and …, 2020 - Elsevier
Difficult healing of skin wounds is one of the serious complications of diabetes mellitus.
Green tea polyphenols (TP) have been found to have good therapeutic effects on wounds …

Mechanisms of diabetic foot ulceration: a review

H Deng, B Li, Q Shen, C Zhang, L Kuang… - Journal of …, 2023 - Wiley Online Library
Diabetic foot ulcers (DFUs) are associated with complex pathogenic factors and are
considered a serious complication of diabetes. The potential mechanisms underlying DFUs …

Function and mechanism of mesenchymal stem cells in the healing of diabetic foot wounds

X Yu, P Liu, Z Li, Z Zhang - Frontiers in Endocrinology, 2023 - frontiersin.org
Diabetes has become a global public health problem. Diabetic foot is one of the most severe
complications of diabetes, which often places a heavy economic burden on patients and …

[HTML][HTML] The role of extracellular matrix in the pathophysiology of diabetic wounds

Y Huang, TR Kyriakides - Matrix biology plus, 2020 - Elsevier
Impaired healing leading to the formation of ulcerated wounds is a critical concern in
patients with diabetes. Abnormalities in extracellular matrix (ECM) production and …

VEGFB promotes myoblasts proliferation and differentiation through VEGFR1-PI3K/Akt signaling pathway

M Ling, L Quan, X Lai, L Lang, F Li, X Yang… - International Journal of …, 2021 - mdpi.com
It has been demonstrated that vascular endothelial growth factor B (VEGFB) plays a vital role
in regulating vascular biological function. However, the role of VEGFB in regulating skeletal …

[HTML][HTML] Exosome mimetics-loaded hydrogel accelerates wound repair by transferring functional mitochondrial proteins

J Zhu, Z Liu, L Wang, Q Jin, Y Zhao, A Du… - … in Bioengineering and …, 2022 - frontiersin.org
Loading human umbilical mesenchymal stem cell (hUMSC) derived exosomes onto
hydrogel scaffolds is a strategy for rapid wound healing. The clinical application of …