Transfer learning in proteins: evaluating novel protein learned representations for bioinformatics tasks

E Fenoy, AA Edera, G Stegmayer - Briefings in Bioinformatics, 2022 - academic.oup.com
A representation method is an algorithm that calculates numerical feature vectors for
samples in a dataset. Such vectors, also known as embeddings, define a relatively low …

Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer

Q Chen, R Menon, LJ Calder, P Tolar… - Nature …, 2022 - nature.com
Immunoglobulin M (IgM) is the most ancient of the five isotypes of immunoglobulin (Ig)
molecules and serves as the first line of defence against pathogens. Here, we use cryo-EM …

Genome-wide CNV investigation suggests a role for cadherin, Wnt, and p53 pathways in primary open-angle glaucoma

V Lo Faro, JB Ten Brink, H Snieder, NM Jansonius… - BMC genomics, 2021 - Springer
Background To investigate whether copy number variations (CNVs) are implicated in
molecular mechanisms underlying primary open-angle glaucoma (POAG), we used …

[图书][B] Perkembangan Dan Manfaat Obat Herbal Sebagai Fitoterapi

W Munaeni, MC Mainassy, D Puspitasari, L Susanti… - 2022 - books.google.com
Fitoterapi pengobatan dan pencegahan penyakit menggunakan tanaman, bagian tanaman,
dan sediaan yang terbuat dari tanaman (tanaman obat/herbal) merupakan bagian penting …

RPEMHC: improved prediction of MHC–peptide binding affinity by a deep learning approach based on residue–residue pair encoding

X Wang, T Wu, Y Jiang, T Chen, D Pan, Z Jin… - …, 2024 - academic.oup.com
Motivation Binding of peptides to major histocompatibility complex (MHC) molecules plays a
crucial role in triggering T cell recognition mechanisms essential for immune response …

Dietary and pharmacological interventions to improve mammalian healthspan and lifespan

L Gkioni - 2023 - kups.ub.uni-koeln.de
Advances in the field of ageing over recent years have led to the discovery that
pharmacological and dietary interventions can slow the ageing process. Genetic alterations …

The effect of Dietary Restriction on the Microbiome and the Adaptive Immune System in Mouse Ageing

C Monzó Cataluña - 2022 - kups.ub.uni-koeln.de
The human body is densely populated by microbes, and the interplay between microbiome
and host physiology is important for health. During ageing, the composition of the …

Identification and characterization of antigen retaining cells in the putative germinal centres of goldfish (Carassius auratus)

A Muthupandian - 2021 - era.library.ualberta.ca
Follicular dendritic cells (FDCs) present within the germinal centres (GCs) capture the
antigen in the form of an immune complex on their cell surface and facilitates the selection of …

Renal cancer detection method and test drug

N Arakawa, H Hirano, N Nakaigawa, M Yao… - US Patent App. 16 …, 2021 - Google Patents
An object of the present invention is to provide a method for detecting renal cancer, and a
reagent that can be used for the method. Provided is a method for detecting renal cancer …

Dinamiche di popolazione del virus della bronchite infettiva aviare (IBV) genotipo QX (GI-19) in Italia

S Leone - thesis.unipd.it
La bronchite infettiva aviare (IB) è una patologia virale dal forte impatto economico e
sanitario su ogni comparto dell'avicoltura mondiale. Essa è causata dal virus della bronchite …