[HTML][HTML] Hypoxia and hypoxia-inducible factors in kidney injury and repair

S Shu, Y Wang, M Zheng, Z Liu, J Cai, C Tang, Z Dong - Cells, 2019 - mdpi.com
Acute kidney injury (AKI) is a major kidney disease characterized by an abrupt loss of renal
function. Accumulating evidence indicates that incomplete or maladaptive repair after AKI …

KIT as a therapeutic target for non-oncological diseases

A Martinez-Anton, D Gras, A Bourdin, P Dubreuil… - Pharmacology & …, 2019 - Elsevier
KIT is a receptor tyrosine kinase that after binding to its ligand stem cell factor activates
signaling cascades linked to biological processes such as proliferation, differentiation …

[HTML][HTML] MicroRNA regulatory pattern in spinal cord ischemia-reperfusion injury

ZG Liu, Y Li, JH Jiao, H Long, ZY Xin… - Neural Regeneration …, 2020 - journals.lww.com
After spinal cord injury, dysregulated miRNAs appear and can participate in inflammatory
responses, as well as the inhibition of apoptosis and axon regeneration through multiple …

[HTML][HTML] Hydrogen protects lung from hypoxia/re-oxygenation injury by reducing hydroxyl radical production and inhibiting inflammatory responses

M Chen, J Zhang, Y Chen, Y Qiu, Z Luo, S Zhao… - Scientific Reports, 2018 - nature.com
Here we investigated whether hydrogen can protect the lung from chronic injury induced by
hypoxia/re-oxygenation (H/R). We developed a mouse model in which H/R exposure …

Low-energy extracorporeal shock wave ameliorates ischemic acute kidney injury in rats

M Yoshida, T Nakamichi, T Mori, K Ito… - Clinical and …, 2019 - Springer
Background Low-energy extracorporeal shock wave (SW) improves ventricular function in
ischemic cardiomyopathy through the upregulation of vascular endothelial growth factor …

Aberrant BMP15/HIF-1α/SCF signaling pathway in human granulosa cells is involved in the PCOS related abnormal follicular development

LY Cao, ZQ Zhang, PP Liu, DF Xu, L Tang… - Gynecological …, 2022 - Taylor & Francis
Aims To investigate the regulatory mechanism of SCF expression in human GCs of PCOS
related follicles. Materials and Methods SCF, BMP15 and HIF-1α were evaluated in human …

The crosstalk between hypoxia-inducible factor-1α and microRNAs in acute kidney injury

Z Wang, W Zhang - Experimental Biology and Medicine, 2020 - journals.sagepub.com
Acute kidney injury (AKI) is a common critical clinical disease that is characterized by a rapid
decline in renal function and reduced urine output. Ischemia and hypoxia are dominant …

Changes and correlations of anti-Müllerian hormone and stem-cell factors in different ovarian reserve patients during GnRH-antagonist protocol and the effects on …

XH Liu, XH Wu, S Yang - Archives of Gynecology and Obstetrics, 2019 - Springer
Purpose To explore the changes and correlations of anti-Müllerian hormone (AMH) and
stem-cell factors (SCF) in different ovarian reserve patients during controlled ovarian …

低氧诱导因子通路在心肾综合征中的作用及低氧诱导因子稳定剂的应用前景

阿柔娜, 何方方, 孙新, 罗长青 - 临床肾脏病杂志, 2022 - lcszb.com
心肾综合征(cardiorenal syndrome, CRS) 是一种多器官疾病, 是指心脏或肾脏其中之一的急性
或慢性功能障碍引起另一器官的急性或慢性功能障碍, 其病理生理涉及免疫炎症, 氧化损伤 …

A novel role of HIF-1α/PROX-1/LYVE-1 axis on tissue regeneration after renal ischaemia/reperfusion in mice

F Meng - Archives of Physiology and Biochemistry, 2019 - Taylor & Francis
Context: Renal ischaemia reperfusion (I/R) is a common clinical condition with a high
morbidity and mortality rate. To date, I/R-induced renal injury remains an ineffective …