As the new SARS-CoV-2 Omicron variants and subvariants emerge, there is an urgency to
develop intranasal, broadly protective vaccines. Here, we developed highly efficacious …

Among the numerous variants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) that have been reported worldwide, the emergence of the Omicron variant has …

Determining SARS-CoV-2 immunity is critical to assess COVID-19 risk and the need for
prevention and mitigation strategies. We measured SARS-CoV-2 Spike/Nucleocapsid …

Objective: Limited data exist regarding the immune benefits of fourth COVID-19 vaccine
doses in people with HIV (PWH) receiving antiretroviral therapy (ART), particularly now that …

Global spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron
subvariants, such as BA. 4, BA. 5 and XBB. 1.5, has been leading the recent wave of …

Abstract The Omicron subvariants BQ. 1.1, XBB. 1.5, and XBB. 1.16 of SARS-CoV-2 are
known for their adeptness at evading immune responses. Here, we isolate a neutralizing …

The emergence of highly immune-escape Omicron variants of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has led to concerns about the efficacy of vaccines …

SARS-CoV-2 continues to pose a threat to public health. Main protease (Mpro) is one of the
most lucrative drug targets for developing specific antivirals against SARS-CoV-2 infection …

Severe acute respiratory disease virus-2 (SARS CoV-2) is one of the deadliest global threats
faced by mankind to date. Despite the colossal efforts, the viral pandemic swept across all …

The continuous emergence of SARS-CoV-2 variants, particularly the newly circulating
Omicron XBB subvariants, has led to a significant reduction in the neutralizing potency and …