[HTML][HTML] Chimeric antigen receptor T-cells: an overview of concepts, applications, limitations, and proposed solutions

A Alnefaie, S Albogami, Y Asiri, T Ahmad… - … in bioengineering and …, 2022 - frontiersin.org
Adaptive immunity, orchestrated by B-cells and T-cells, plays a crucial role in protecting the
body from pathogenic invaders and can be used as tools to enhance the body's defense …

[HTML][HTML] Immunotherapy for hepatocellular carcinoma: current status and future prospects

Z Liu, X Liu, J Liang, Y Liu, X Hou, M Zhang… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer with poor
prognosis. Surgery, chemotherapy, and radiofrequency ablation are three conventional …

[HTML][HTML] Targeting immune cells in the tumor microenvironment of HCC: new opportunities and challenges

X Hao, G Sun, Y Zhang, X Kong, D Rong… - Frontiers in cell and …, 2021 - frontiersin.org
Immune associated cells in the microenvironment have a significant impact on the
development and progression of hepatocellular carcinoma (HCC) and have received more …

[HTML][HTML] CAR T cell-based immunotherapy for the treatment of glioblastoma

L Maggs, G Cattaneo, AE Dal… - Frontiers in …, 2021 - frontiersin.org
Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain
tumor in adults. Current treatment options typically consist of surgery followed by …

CAR‐NK cell in cancer immunotherapy; A promising frontier

F Marofi, OF Abdul‐Rasheed, HS Rahman… - Cancer …, 2021 - Wiley Online Library
Chimeric antigen receptors (CARs) have a unique facet of synthetic biology and offer a
paradigm shift in personalized medicine as they can use and redirect the patient's immune …

[HTML][HTML] Immunotherapy for hepatocellular carcinoma: Current status and future perspectives

DS Mandlik, SK Mandlik… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the world's deadliest and fastest-growing tumors,
with a poor prognosis. HCC develops in the context of chronic liver disease. Curative …

[PDF][PDF] RETRACTED: CAR-NK Cell: A New Paradigm in Tumor Immunotherapy

F Marofi, AS Al-Awad, H Sulaiman Rahman… - Frontiers in …, 2021 - frontiersin.org
The tumor microenvironment (TME) is greatly multifaceted and immune escape is an
imperative attribute of tumors fostering tumor progression and metastasis. Based on reports …

[HTML][HTML] Development of NK cell-based cancer immunotherapies through receptor engineering

A Page, N Chuvin, J Valladeau-Guilemond… - Cellular & Molecular …, 2024 - nature.com
Natural killer (NK) cell-based immunotherapies are attracting increasing interest in the field
of cancer treatment. Early clinical trials have shown promising outcomes, alongside …

[HTML][HTML] Tumor buster-where will the CAR-T cell therapy 'missile'go?

C Qu, H Zhang, H Cao, L Tang, H Mo, F Liu, L Zhang… - Molecular Cancer, 2022 - Springer
Chimeric antigen receptor (CAR) T cell (CAR-T cell) therapy based on gene editing
technology represents a significant breakthrough in personalized immunotherapy for human …

[HTML][HTML] Combination of ablation and immunotherapy for hepatocellular carcinoma: where we are and where to go

K Wang, C Wang, H Jiang, Y Zhang, W Lin… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide and is increasing in incidence. Local ablative therapy plays a leading role in HCC …