Soluble HLA-G: Are they clinically relevant?

V Pistoia, F Morandi, X Wang, S Ferrone - Seminars in cancer biology, 2007 - Elsevier
HLA-G is a non-classical HLA-class Ib molecule with multiple immunoregulatory properties.
Its main function in physiological conditions is to abrogate maternal NK cell activity against …

A Comprehensive Study of Polymorphic Sites along the HLA-G Gene: Implication for Gene Regulation and Evolution

EC Castelli, CT Mendes-Junior… - Molecular biology …, 2011 - academic.oup.com
HLA-G molecule plays an important role on immune response regulation and has been
implicated on the inhibition of T and natural killer cell cytolytic function and inhibition of …

Biology of HLA-G in cancer: a candidate molecule for therapeutic intervention?

L Amiot, S Ferrone, H Grosse-Wilde… - Cellular and Molecular Life …, 2011 - Springer
Although the expression of the non-classical HLA class I molecule HLA-G was first reported
to be restricted to the fetal–maternal interface on the extravillous cytotrophoblasts, the …

HLA-G molecules in autoimmune diseases and infections

R Rizzo, D Bortolotti, S Bolzani, E Fainardi - Frontiers in immunology, 2014 - frontiersin.org
Human leukocyte antigen (HLA)-G molecule, a non-classical HLA-Ib molecule, is less
polymorphic when compared to classical HLA class I molecules. Human leukocyte antigen …

Embryonic soluble HLA-G as a marker of developmental potential in embryos

I Noci, B Fuzzi, R Rizzo, L Melchiorri… - Human …, 2005 - academic.oup.com
BACKGROUND: In human reproduction, embryo implantation is complex and poorly
understood. At present, no single markers are used in routine treatment to assay …

In silico analysis of microRNAS targeting the HLA-G 3′ untranslated region alleles and haplotypes

EC Castelli, P Moreau, AO e Chiromatzo… - Human immunology, 2009 - Elsevier
It has been reported that microRNAs (miRNA) may have allele-specific targeting for the 3′
untranslated region (3′ UTR) of the HLA-G locus. In a previous study, we reported 11 3 …

HLA‐G as a tolerogenic molecule in transplantation and pregnancy

V Rebmann, F da Silva Nardi… - Journal of …, 2014 - Wiley Online Library
HLA‐G is a nonclassical HLA class I molecule. In allogeneic situations such as pregnancy or
allograft transplantation, the expression of HLA‐G has been related to a better acceptance of …

HLA associations and HLA sharing in recurrent miscarriage: a systematic review and meta-analysis

T Meuleman, LELO Lashley, OM Dekkers… - Human immunology, 2015 - Elsevier
Problem The aim of this meta-analysis was to evaluate whether specific maternal HLA
alleles and HLA sharing of couples are associated with the occurrence of recurrent …

The dual role of HLA‐G in cancer

N Rouas-Freiss, P Moreau, J LeMaoult… - Journal of …, 2014 - Wiley Online Library
We here review the current data on the role of HLA‐G in cancer based on recent findings of
an unexpected antitumor activity of HLA‐G in hematological malignancies. For the past …

HLA‐G genotype and HLA‐G expression in systemic lupus erythematosus: HLA‐G as a putative susceptibility gene in systemic lupus erythematosus

R Rizzo, TVF Hviid, M Govoni, M Padovan… - Tissue …, 2008 - Wiley Online Library
Systemic lupus erythematosus (SLE) is an autoimmune disease mainly mediated by the
deposit of immune complexes and defects in T lymphocytes and antigen‐presenting cells …