Introduction A large number of risk and protective factors have been identified during the
SARS-CoV-2 pandemic which may influence the outcome of COVID-19. Among these …

Introduction• HLA‐G gene promoter region: regulatory sites and binding factors‐The atypical
proximal promoter region of the HLA‐G gene among classical HLA class I genes‐Alternative …

Pregnancy in mammals featuring hemochorial placentation introduces a major conflict with
the mother's immune system, which is dedicated to repelling invaders bearing foreign DNA …

The HLA class Ib genes, HLA-E, HLA-F, and HLA-G, were discovered long after the classical
HLA class Ia genes. The elucidation of their functions had a modest beginning. However …

BACKGROUND The human leucocyte antigen (HLA) class Ib molecules, HLA-E,-F and-G,
are expressed at the materno-fetal interface. Because of the apparent immunoregulatory …

Reproductive failure in humans is a very important social and economic problem, because
nowadays women decide to conceive later in life and delay motherhood. Unfortunately, with …

The HLA-G (human leukocyte antigen-G) molecule plays a pivotal role in immune tolerance
by inhibiting different cell subsets involved in both innate and adaptive immunity. Besides its …

Preeclampsia is a pregnancy-induced hypertensive disorder, the pathophysiology of which
includes underlying maternal cardiovascular disease, deficient spiral artery remodeling …

Abstract Classical HLA (Human Leukocyte Antigen) is the Major Histocompatibility Complex
(MHC) in man. HLA genes and disease association has been studied at least since 1967 …

Human leukocyte antigen-G (HLA-G) is a nonclassical class I major histocompatibility
complex molecule which is induced at the course of inflammatory pathologies, and its …