Abstract Purpose The HLA-G 14-bp insertion/deletion polymorphism had been
inconsistently associated with recurrent miscarriage (RM) risk. We examined the association …

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease that affects
several organs and systems. Its etiology remains unknown, although it is probably …

Human leukocyte antigen (HLA)-G is an MHC class Ib molecule that is expressed at the feto-
maternal interface during pregnancy. However, recent results have also shown that it may …

The immune checkpoint HLA-G prevents maternal rejection of the fetus and contributes in
cancer invasion and acceptance of allografts. The 5'and 3'regulatory regions of the HLA-G …

Aims: Clinical response to methotrexate (MTX) treatment differs among rheumatoid arthritis
patients. Genetic variation can partly account for this phenomenon. In this study, functional …

The current management of early rheumatoid arthritis (ERA) is to start an intensive treatment
as soon as possible. To avoid under/overtreatment, it is important to identify reliable ERA …

HLA-G is believed to act as an anti-inflammatory molecule in Multiple Sclerosis (MS). The
3′ untranslated region of the HLA-G gene is characterized by two polymorphisms …

Homozygous carriage of a 14 base pair (bp) insertion in exon 8 of the HLA-G gene may be
associated with low levels of soluble HLA-G and recurrent miscarriage (RM). We …

This work investigates the possibility that HLA-G, a molecule modulating innate and
adaptive immunity, is part of an immune escape strategy of chronic lymphocytic leukemia …

Human Leukocyte Antigen (HLA)-G is an immunosuppressive molecule acting on both the
innate and adaptive immune system. A 14bp insertion/deletion polymorphism (rs66554220) …