Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration.
Synovial inflammation is present in the OA joint and has been associated with radiographic …

Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …

Pain is the major symptom of osteoarthritis (OA) and is an important factor in strategies to
manage this disease. However, the current standard of care does not provide satisfactory …

Chronic, low-grade inflammation in osteoarthritis (OA) contributes to symptoms and disease
progression. Effective disease-modifying OA therapies are lacking, but better understanding …

The increased information provided by modern imaging has led to its more extensive use.
Our aim was to develop evidence-based recommendations for the use of imaging in the …

Osteoarthritis (OA) has long been considered the unique consequence of a wear and tear
process leading to cartilage degradation. Indeed, it is true that excessive mechanical stress …

Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

Objective. To get a better understanding of inflammatory pathways active in the osteoarthritic
(OA) joint, we characterized and compared inflammatory cells in the synovium and the …

Objective To investigate the presence of mast cells in the osteoarthritic (OA) synovium and
their association with clinical parameters in comparison with rheumatoid arthritis (RA) …

Background: Platelet-rich plasma (PRP) has emerged as the forerunner among disease-
modifying treatment options for early osteoarthritis (OA) of the knee. However, no consensus …