Regulation of cation channels in cardiac and smooth muscle cells by intracellular magnesium
K Mubagwa, A Gwanyanya, S Zakharov… - Archives of biochemistry …, 2007 - Elsevier
Magnesium regulates various ion channels in many tissues, including those of the
cardiovascular system. General mechanisms by which intracellular Mg2+ (Mgi2+) regulates …
cardiovascular system. General mechanisms by which intracellular Mg2+ (Mgi2+) regulates …
Distinct properties of CRAC and MIC channels in RBL cells
JA Kozak, HH Kerschbaum, MD Cahalan - The Journal of general …, 2002 - rupress.org
In rat basophilic leukemia (RBL) cells and Jurkat T cells, Ca2+ release–activated Ca2+
(CRAC) channels open in response to passive Ca2+ store depletion. Inwardly rectifying …
(CRAC) channels open in response to passive Ca2+ store depletion. Inwardly rectifying …
Structure-function studies of voltage-gated ion channels
W Stühmer - Annual review of biophysics and biophysical …, 1991 - annualreviews.org
The rapid development of molecular biology techniques during recent years has opened up
novel possibilities for the study of ion channels at a molecular level. The elucidation of …
novel possibilities for the study of ion channels at a molecular level. The elucidation of …
Extracellular Mg2+ regulates activation of rat eag potassium channel
H Terlau, J Ludwig, R Steffan, O Pongs, W Stühmer… - Pflügers Archiv, 1996 - Springer
The rat homologue of Drosophila ether à gogo cDNA (rat eag) encodes voltage-activated
potassium (K) channels with distinct activation properties. Using the Xenopus expression …
potassium (K) channels with distinct activation properties. Using the Xenopus expression …
Inward rectifier potassium channels in plants differ from their animal counterparts in response to voltage and channel modulators
We have investigated the electrophysiological basis of potassium inward rectification of the
KAT1 gene product from Arabidopsis thaliana expressed in Xenopus oocytes and of …
KAT1 gene product from Arabidopsis thaliana expressed in Xenopus oocytes and of …
Monovalent permeability, rectification, and ionic block of store-operated calcium channels in Jurkat T lymphocytes
HH Kerschbaum, MD Cahalan - The Journal of general physiology, 1998 - rupress.org
We used whole-cell recording to characterize ion permeation, rectification, and block of
monovalent current through calcium release-activated calcium (CRAC) channels in Jurkat T …
monovalent current through calcium release-activated calcium (CRAC) channels in Jurkat T …
[PDF][PDF] Cytoplasmic polyamines as permeant blockers and modulators of the voltage-gated sodium channel
CJ Huang, E Moczydlowski - Biophysical Journal, 2001 - cell.com
We report that voltage-gated Na+ channels (Na V) from rat muscle (μ1) expressed in
HEK293 cells exhibit anomalous rectification of whole-cell outward current under conditions …
HEK293 cells exhibit anomalous rectification of whole-cell outward current under conditions …
Single point mutations of the sodium channel drastically reduce the pore permeability without preventing its gating
M Pusch, M Noda, W Stühmer, S Numa… - European biophysics …, 1991 - Springer
Two mutants of the sodium channel II have been expressed in Xenopus oocytes and have
been investigated using the patch-clamp technique. In mutant E387Q the glutamic acid at …
been investigated using the patch-clamp technique. In mutant E387Q the glutamic acid at …
Microvillar ion channels: cytoskeletal modulation of ion fluxes
K Lange - Journal of Theoretical Biology, 2000 - Elsevier
The recently presented theory of microvillar Ca2+ signaling [Lange, K.(1999) J. Cell. Physiol.
180, 19–35], combined with Manning's theory of “condensed counterions” in linear …
180, 19–35], combined with Manning's theory of “condensed counterions” in linear …
Ca2+ and Na+ permeability of high‐threshold Ca2+ channels and their volt age‐dependent block by Mg2+ ions in chick sensory neurones
E Carbone, HD Lux, V Carabelli… - The Journal of …, 1997 - Wiley Online Library
1 The Mg2+ block of Na+ and Ca2+ currents through high‐voltage activated (HVA; L‐and N‐
type) Ca2+ channels was studied in chick dorsal root ganglion neurones. 2 In low …
type) Ca2+ channels was studied in chick dorsal root ganglion neurones. 2 In low …