Interleukin-17 (IL-17) is an essential proinflammatory cytokine, which is mainly secreted by
the CD4+ helper T cells (Th17 cells) and subsets of innate lymphoid cells. IL-17A is …

Background Alopecia areata is a disorder that results in nonscarring hair loss. The
psychological impact can be significant, leading to feelings of depression and social …

Alopecia areata (AA) is a relatively common nonscarring hairloss disease characterized by
an autoimmune response to anagen hair follicles (HFs). Accumulated evidence suggests …

Alopecia areata is a type of non-scarring hair loss. The dysregulation of numerous systemic
Th1 (IL-2, IFN-γ, TNF, IL-12, and IL-18), Th2 (IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17E, IL-31 …

Alopecia areata is an autoimmune hair loss disease that is non-scarring and is
characterized by chronic inflammation at the hair follicle level. Clinically, patients' …

Studies on the role of interleukins (ILs) in autoimmune and inflammatory diseases allow for
the better understanding of pathologic mechanisms of disease and reshaping of treatment …

Background Parkinson's disease (PD) is the second most common neurodegenerative
disease in the world. Various studies have suggested that the immune response plays a key …

Background Alopecia areata (AA) is a common autoimmune disease, causing patchy hair
loss that can progress to involve the entire scalp (totalis) or body (universalis). CD8+ …

Alopecia areata (AA), a prevalent inflammatory cause of hair loss, lacks FDA-approved
therapeutics for extensive cases, which are associated with very poor rates of spontaneous …

Summary Interleukin (IL)‐17 is an emerging target for inflammatory skin disorders. Given the
remarkable success of its therapeutic inhibition in psoriasis, the pathogenic role of this …