Transcriptomic data analysis coupled with copy number aberrations reveals a blood-based 17-gene signature for diagnosis and prognosis of patients with colorectal …

IH Kaya, O Al-Harazi, D Colak - Frontiers in genetics, 2023 - frontiersin.org
Background: Colorectal cancer (CRC) is the third most common cancer and third leading
cause of cancer-associated deaths worldwide. Diagnosing CRC patients reliably at an early …

Astragaloside IV suppresses hepatic proliferation in regenerating rat liver after 70% partial hepatectomy via down-regulation of cell cycle pathway and DNA replication

GS Lee, HY Jeong, HG Yang, YR Seo, EG Jung… - Molecules, 2021 - mdpi.com
Astragaloside IV (AS-IV) is one of the major bio-active ingredients of huang qi which is the
dried root of Astragalus membranaceus (a traditional Chinese medicinal plant). The …

[HTML][HTML] Single-cell RNA sequencing reveals homogeneous transcriptome patterns and low variance in a suspension CHO-K1 and an adherent HEK293FT cell line in …

G Borsi, K Motheramgari, H Dhiman, M Baumann… - Journal of …, 2023 - Elsevier
Recombinant mammalian host cell lines, in particular CHO and HEK293 cells, are used for
the industrial production of therapeutic proteins. Despite their well-known genomic …

[HTML][HTML] Human embryonic stem cell-derived immunity-and-matrix regulatory cells promote intrahepatic cell renewal to rescue acute liver failure

L Chen, Z Li, W Wei, B An, Y Tian, W Liu, S Niu… - Biochemical and …, 2023 - Elsevier
Acute liver failure (ALF) is a clinical syndrome characterized by the accelerated
development of hepatocyte necrosis and significant mortality. Given that liver transplantation …

[PDF][PDF] ALPPS 动物模型构建及相关研究的新进展

陈穴, 陈耿 - 中国比较医学杂志, 2022 - zgbjyx.cnjournals.com
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
accelerates liver regeneration remarkably. However, the molecular mechanism of ALPPS …

Effects of Sodium Chromate Exposure on Gene Expression Profiles of Primary Rat Hepatocytes (In Vitro)

X Li, AME Abdel-Moneim, J Hua, L Zhao, Z Hu… - … Trace Element Research, 2023 - Springer
Chromium exposure has adverse impacts on human health and the environment, whereas
chromate-induced hepatotoxicity's detailed mechanism is still unclear. Therefore, the …

联合肝脏离断和门静脉结扎的二步肝切除术后肝再生机制

曾陶飞, 陈光磊, 刘彩刚, 戴朝六, 徐锋 - 临床肝胆病杂志, 2020 - lcgdbzz.org
肝切除术后剩余肝脏(FLR) 体积不足常导致肝衰竭等并发症, 甚至死亡, 是肝脏外科亟需解决的
瓶颈问题之一. 联合肝脏离断和门静脉结扎的二步肝切除术(ALPPS) 是近年兴起的二步肝切除术 …

[PDF][PDF] 不同肝血流阻断方式肝切除手术对原发性肝癌合并肝硬化患者肝功能及肠黏膜屏障的影响

莫庆荣, 翁俊, 李淑群, 喻亚群… - Progress in Modern …, 2020 - biomed.cnjournals.com
摘要目的: 探讨肝切除手术运用Pringle 法阻断, 半肝血流阻断(HVC) 后对原发性肝癌合并肝硬化
患者肝功能及肠黏膜屏障的影响. 方法: 选取2016 年4 月~ 2019 年9 月期间我院收治的原发性 …

Developing Methods to Detect Dna Repair Defects in a Diverse Population

MA Smith - 2022 - search.proquest.com
Primary liver cancer, including hepatocellular carcinoma (HCC) and cholangiocarcinoma
(CCA), is one of the fastest growing cancer types. Although HCCs and CCAs are …

Investigating the effect of IL-17 on ductular reaction during liver regeneration

E Ward - 2022 - etheses.bham.ac.uk
NAFLD is a highly prevalent disease, currently affecting an estimated 25% of the global
population. Liver transplantation remains the only curative treatment, but this is becoming …