Not only the 24 or so essential elements, but also nonessential and even radioactive
elements have enormous potential for applications in medicine. In the fight against cancer …

In the next two decades, the world is expected to see around 20 million cases of cancer.
Moreover, the types of cancer will vary considerably from country to other. Therefore, all …

第3代铂类药物洛铂的研究新进展 Page 1 ·综述与讲座· 第3代铂类药物洛铂的研究新进展' ' 基金
项目:国家“863”计划重点课题资助项目(2006AA020608) 210002 南京解放军八一医院全军肿瘤 …

Publisher Summary Biomedical inorganic chemistry “Elemental Medicine” is an important
new area of chemistry. Platinum complexes are now among the most widely used drugs for …

Lobaplatin (D-19466) is a diastereometric mixture of platinum (II) complexes containing a 1,
2-bis (aminomethyl) cyclobutane stable ligand and lactic acid as the leaving group. Its …

Following the serendipitous discovery of the anticancer drug, cisplatin, numerous platinum
(II) complexes have been synthesized and some of them, such as carboplatin, oxaliplatin …

Platinum drugs have been coined as one of the great success representatives in cancer
chemotherapy. With the accidental discovery of cisplatin, thousands of platinum-based …

Most of the structure/activity rules emerged from the initial studies by Rosenberg and Cleare
and Hoeschele have now been questioned. Specifically:(i) trans compounds are inactive,(ii) …

Cisplatin and its platinum (Pt)(II) derivatives play a key role in the fight against various
human cancers such as testicular, ovarian, head and neck, lung tumors. However, their …

Nicht nur die etwa 24 essentiellen Elemente, sondern auch nichtessentielle und sogar
radioaktive Elemente verfügen über ein enormes medizinisches Potential. Im Kampf gegen …