Cdc14-family phosphatases play a conserved role in promoting mitotic exit and cytokinesis
by dephosphorylating substrates of cyclin-dependent kinase (Cdk). Cdc14-family …

In eukaryotes, cytokinesis generally involves an actomyosin ring, the contraction of which
promotes daughter cell segregation. Assembly of the contractile ring is tightly controlled in …

Members of C dc14 phosphatases are common in animals and fungi, but absent in plants.
Although its orthologs are conserved in plant pathogenic fungi, their functions during …

We will briefly introduce the S. pombe model, giving references to reviews addressing
aspects of fission yeast biology that are beyond the scope of this overview. As their common …

Cytokinesis gives rise to two independent daughter cells at the end of the cell division cycle.
The fission yeast Schizosaccharomyces pombe has emerged as one of the most powerful …

Cytokinesis is the final stage of cell division cycle when cellular constituents are separated
to produce two daughter cells. This process is driven by the formation and constriction of a …

The scaffolding protein anillin is required for completion of cytokinesis. Anillin binds
filamentous (F) actin, nonmuscle myosin II, and septins and in cell culture models has been …

Many eukaryotes accomplish cell division by building and constricting a medial actomyosin-
based cytokinetic ring (CR). In Schizosaccharomyces pombe, a Hippo-related signaling …

The Cdc14 phosphatase family is highly conserved in fungi. In Saccharomyces cerevisiae,
Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit …

Paxillin is a scaffold protein that participates in focal adhesion signaling in mammalian cells.
Fission yeast paxillin ortholog, Pxl1, is required for contractile actomyosin ring (CAR) …