Identification of individuals at risk for postoperative cognitive dysfunction (POCD)

X Yang, X Huang, M Li, Y Jiang… - Therapeutic advances …, 2022 - journals.sagepub.com
Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of
individuals within first few weeks after surgery. Although the majority of POCD is less …

Postoperative outcomes in older surgical patients with preoperative cognitive impairment: A systematic review and meta-analysis

L Chen, E Au, A Saripella, P Kapoor, E Yan… - Journal of Clinical …, 2022 - Elsevier
Study objective To determine the effect of cognitive impairment (CI) and dementia on
adverse outcomes in older surgical patients. Design A systematic review and meta-analysis …

Prevalence of preoperative cognitive impairment in older surgical patients.: A systematic review and meta-analysis

P Kapoor, L Chen, A Saripella, R Waseem… - Journal of clinical …, 2022 - Elsevier
Study objective Older surgical patients with cognitive impairment are at an increased risk for
adverse perioperative outcomes, however the prevalence of preoperative cognitive …

Does preoperative cognitive optimization improve postoperative outcomes in the elderly?

Y Ishizawa - Journal of Clinical Medicine, 2022 - mdpi.com
Perioperative neurocognitive disorder (PND) is a growing concern, affecting several million
elderly patients each year in the United States, but strategies for its effective prevention have …

Geriatric assessment and medical preoperative screening (GrAMPS) program for older hernia patients

BS Kushner, J Hamilton, BJ Han, M Sehnert, T Holden… - Hernia, 2021 - Springer
Purpose The incidence of older adults undergoing inguinal and ventral hernia repairs is
increasing. Older adults are disproportionately affected by age-related risk factors, which are …

Atorvastatin attenuates surgery-induced BBB disruption and cognitive impairment partly by suppressing NF-κB pathway and NLRP3 inflammasome activation in aged …

P Liu, Q Gao, L Guan, Y Hu, J Jiang… - Acta Biochimica et …, 2021 - academic.oup.com
In clinic, perioperative neurocognitive disorder is becoming a common complication of
surgery in old patients. Neuroinflammation and blood–brain barrier (BBB) disruption are …

Effects of different injection rates of propofol on postoperative cognition in elderly patients undergoing laparoscopic inguinal hernia repair

T Li, W Han, X Yang, Y Wang, L Peng… - Drug Design …, 2023 - Taylor & Francis
Purpose This study aimed to explore the effects of different injection rates of propofol on
postoperative cognition in elderly patients undergoing laparoscopic inguinal hernia repair …

Pre-Therapeutic Assessment of Older People in Sub-Saharan Africa: Introduction to the Comprehensive Geriatric Assessment

MJ Ntsama Essomba, BS Esson Mapoko… - Journal of Clinical …, 2024 - mdpi.com
Objectives: With the ongoing epidemiological transition in sub-Saharan Africa (SSA),
conditions that require invasive treatment (surgery, cancer, and anaesthesia, etc.) will …

Preexisting dementia is associated with increased risks of mortality and morbidity following major surgery: A nationwide propensity score matching study

YM Wu, HC Kuo, CC Li, HL Wu, JT Chen… - International journal of …, 2020 - mdpi.com
Patients with dementia are predisposed to multiple physiological abnormalities. It is
uncertain if dementia associates with higher rates of perioperative mortality and morbidity …

Delirium in older adults: what a surgeon needs to know

G Melegari, A Gaspari, E Gualdi, M Zoli, S Meletti… - Surgeries, 2022 - mdpi.com
Delirium remains a challenging clinical problem in hospitalized older adults, especially for
postoperative patients. This complication, with a high risk of postoperative mortality and an …