Tyrosinase is a copper-containing oxidation enzyme, which is responsible for the production
of melanin. This enzyme is widely distributed in microorganisms, animals and plants, and …

The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …

An iridium‐catalyzed reductive three‐component coupling reaction for the synthesis of
medicinally relevant α‐amino 1, 3, 4‐oxadiazoles from abundant tertiary amides or lactams …

The reaction of 5-(3, 4-dimethoxyphenyl)-1, 3, 4-oxadiazole-2 (3 H)-thione 3 with
formaldehyde solution and primary aromatic amines or 1-substituted piperazines, in ethanol …

Green synthetic protocol refers to the development of processes for the sustainable
production of chemicals and materials. For the synthesis of various biologically active …

Due to the biological importance of thienopyrimidine derivatives, we present here a synthetic
way for the design of new thienopyrimidines (2‒11) using the precursor 2-(4-Oxo-9-phenyl …

Finding an effective anti-Alzheimer agent is quite challenging due to its multifactorial nature.
As such, multitarget directed ligands (MTDLs) could be a promising paradigm for finding …

The multiple inhibition of biological targets involved in pro-inflammatory eicosanoid
biosynthesis represents an innovative strategy for treating inflammatory disorders in light of …

1, 3, 4-Oxadiazole moiety is a crucial pharmacophore in many biologically active
compounds. In a typical synthesis, probenecid was subjected to a sequence of reactions to …

Malaria remains a prevalent infectious disease in developing countries. The first-line
therapeutic options are based on combinations of fast-acting artemisinin derivatives and …