[HTML][HTML] Epigenetic reprogramming during somatic cell nuclear transfer: recent progress and future directions

X Wang, J Qu, J Li, H He, Z Liu, Y Huan - Frontiers in Genetics, 2020 - frontiersin.org
Somatic cell nuclear transfer (SCNT) has broad applications but is limited by low cloning
efficiency. In this review, we mainly focus on SCNT-mediated epigenetic reprogramming in …

[HTML][HTML] Strategies to improve the efficiency of somatic cell nuclear transfer

K Srirattana, M Kaneda, R Parnpai - International Journal of Molecular …, 2022 - mdpi.com
Mammalian oocytes can reprogram differentiated somatic cells into a totipotent state through
somatic cell nuclear transfer (SCNT), which is known as cloning. Although many mammalian …

[HTML][HTML] Generating cloned goats by somatic cell nuclear transfer—Molecular determinants and application to transgenics and biomedicine

M Skrzyszowska, M Samiec - International journal of molecular sciences, 2021 - mdpi.com
The domestic goat (Capra aegagrus hircus), a mammalian species with high genetic merit
for production of milk and meat, can be a tremendously valuable tool for transgenic …

Aberrant DNA and histone methylation during zygotic genome activation in goat cloned embryos

M Deng, Z Liu, B Chen, Y Wan, H Yang, Y Zhang, Y Cai… - Theriogenology, 2020 - Elsevier
In somatic cell nuclear transfer (SCNT) embryos, developmental defects first appear at the
time of zygotic genome activation (ZGA), a process that is under the control of DNA and …

[HTML][HTML] Manipulating the epigenome in nuclear transfer cloning: Where, when and how

K Simmet, E Wolf, V Zakhartchenko - International Journal of Molecular …, 2020 - mdpi.com
The nucleus of a differentiated cell can be reprogrammed to a totipotent state by exposure to
the cytoplasm of an enucleated oocyte, and the reconstructed nuclear transfer embryo can …

[HTML][HTML] Enhancement of Chromatin and Epigenetic Reprogramming in Porcine SCNT Embryos—Progresses and Perspectives

WG Glanzner, MP de Macedo, K Gutierrez… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the last 25 years, cloned animals have been produced by transferring somatic cell
nuclei into enucleated oocytes (SCNT) in more than 20 mammalian species. Among …

Chromatin architecture reorganization during somatic cell reprogramming

K Zhao, M Wang, S Gao, J Chen - Current Opinion in Genetics & …, 2021 - Elsevier
It has been nearly 60 years since Dr John Gurdon achieved the first cloning of Xenopus by
somatic cell nuclear transfer (SCNT). Later, in 2006, Takahashi and Yamanaka published …

Comparison of pregnancy rates with transfer of in vivo produced embryos derived using multiple ovulation and embryo transfer (MOET) with in vitro produced embryos …

BS Vettical, SB Hong, MA Umer, NA Wani - Animal reproduction science, 2019 - Elsevier
In the present study, there was comparison of pregnancy rates with transfer of in vivo-
produced embryos using multiple ovulation and embryo transfer (MOET) with in vitro …

Reproductive biotechnologies applied to the female sheep and goat

JMG Souza-Fabjan, BRC Alves, RITP Batista… - … Agriculture Reviews 59 …, 2023 - Springer
Applying reproductive biotechnologies to female sheep and goats allows to improving
animal protein production, advancing scientific knowledge with the use of small ruminants …

[HTML][HTML] A long non-coding RNA essential for early embryonic development improves somatic cell nuclear transfer somatic cell nuclear transfer efficiency in goats

M Jin, L Zhao, H Yang, J Zhao, H Ma, Y Chen… - …, 2023 - rep.bioscientifica.com
In brief Early embryonic development in goats is a complex and an important process. This
study identified a novel long non-coding RNA (lncRNA), lncRNA3720, that appears to affect …