Pathology of endometrioid and clear cell carcinoma of the ovary

O Fadare, V Parkash - Surgical pathology clinics, 2019 - surgpath.theclinics.com
This review is an appraisal of the current state of knowledge of 2 enigmatic histotypes of
ovarian carcinoma: endometrioid and clear cell carcinoma. Both show an association …

Abnormally located SSEA1+/SOX9+ endometrial epithelial cells with a basalis-like phenotype in the eutopic functionalis layer may play a role in the pathogenesis of …

DK Hapangama, J Drury, L Da Silva… - Human …, 2019 - academic.oup.com
STUDY QUESTION Is endometriosis associated with abnormally located endometrial
basalis-like (SSEA1+/SOX9+) cells in the secretory phase functionalis and could they …

Endometriosis-associated ovarian cancer: What have we learned so far?

M Herreros-Villanueva, CC Chen, EM Tsai, TK Er - Clinica Chimica Acta, 2019 - Elsevier
Endometriosis is defined as the presence of ectopic endometrial tissue outside of the uterine
cavity, most commonly in the ovaries and peritoneum. It is a complex disease that is …

[HTML][HTML] Endometriosis in the era of precision medicine and impact on sexual and reproductive health across the lifespan and in diverse populations

LC Giudice, TT Oskotsky, S Falako… - The FASEB …, 2023 - ncbi.nlm.nih.gov
Endometriosis is a common estrogen‐dependent disorder wherein uterine lining tissue
(endometrium) is found mainly in the pelvis where it causes inflammation, chronic pelvic …

Biological characteristics of endometriotic mesenchymal stem cells isolated from ectopic lesions of patients with endometriosis

Y Liu, S Liang, F Yang, Y Sun, L Niu, Y Ren… - Stem Cell Research & …, 2020 - Springer
Background Research into the pathogenesis of endometriosis (EMs) would substantially
promote its effective treatment and early diagnosis. However, the aetiology of EMs is poorly …

Tissue specific regulation of transcription in endometrium and association with disease

S Mortlock, RI Kendarsari, JN Fung… - Human …, 2020 - academic.oup.com
STUDY QUESTION Are genetic effects on endometrial gene expression tissue specific
and/or associated with reproductive traits and diseases? SUMMARY ANSWER Analyses of …

KRAS mutations and endometriosis burden of disease

NL Orr, A Albert, YD Liu, A Lum… - The Journal of …, 2023 - Wiley Online Library
The clinical phenotype of somatic mutations in endometriosis is unknown. The objective was
to determine whether somatic KRAS mutations were associated with greater disease burden …

Genome‐wide mutation analysis in precancerous lesions of endometrial carcinoma

L Li, P Yue, Q Song, TT Yen, S Asaka… - The Journal of …, 2021 - Wiley Online Library
Clinicopathological evidence supports endometrial atypical hyperplasia (AH) or endometrial
intraepithelial neoplasia as the precursor of uterine endometrioid carcinoma (EC), the most …

Should genetics now be considered the pre-eminent etiologic factor in endometriosis?

GW Montgomery, S Mortlock, LC Giudice - Journal of minimally invasive …, 2020 - Elsevier
Endometriosis is a common, estrogen-dependent, inflammatory disorder characterized by
the growth of endometrial-like tissue at extrauterine locations. Its pathogenesis and …

Clonal lineage from normal endometrium to ovarian clear cell carcinoma through ovarian endometriosis

K Suda, LA Cruz Diaz, K Yoshihara, H Nakaoka… - Cancer …, 2020 - Wiley Online Library
Clear cell carcinoma of the ovary is thought to arise from endometriosis. In addition,
retrograde menstruation of shed endometrium is considered the origin of endometriosis …