Oxidative stress (OS) disrupts the chemical integrity of macromolecules and increases the
risk of neurodegenerative diseases. Fisetin is a flavonoid that exhibits potent antioxidant …

Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

Saponins are triterpenoid or steroidal glycosides and are an important group of naturally
occurring compounds of plant origin. They exhibit diverse pharmacological potentials …

Turmeric, or Curcuma longa as it is formally named, is a multifunctional plant with numerous
names. It was dubbed “the golden spice” and “Indian saffron” not only for its magnificent …

It is estimated that, at minimum, 500 million individuals suffer from cellular metabolic
dysfunction, such as diabetes mellitus (DM), throughout the world. Even more concerning is …

Almost three million individuals suffer from multiple sclerosis (MS) throughout the world, a
demyelinating disease in the nervous system with increased prevalence over the last five …

Disorders of metabolism affect multiple systems throughout the body, but may have the
greatest impact on both central and peripheral nervous systems. Current available …

Life expectancy is increasing throughout the world and coincides with a rise in non-
communicable diseases (NCDs), especially for metabolic disease that includes diabetes …

Erythropoietin (EPO) is a clinically significant four-helical cytokine, exhibiting erythropoietic,
cytoprotective, immunomodulatory, and cancer-promoting activities. Despite vast knowledge …

Currently, acetylcholinesterase (AChE) inhibiting drugs in clinical use, such as tacrine,
donepezil, rivastigmine, and galanthamine, are associated with serious side effects and …