Sustainable lignin and lignin-derived compounds as potential therapeutic agents for degenerative orthopaedic diseases: A systemic review

W Pei, J Deng, P Wang, X Wang, L Zheng… - International journal of …, 2022 - Elsevier
Lignin, the most abundant natural and sustainable phenolic compound in biomass, has
exhibited medicinal values due to its biological activities decided by physicochemical …

The role of genetics and epigenetic regulation in the pathogenesis of osteoarthritis

K Kiełbowski, M Herian, E Bakinowska… - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is progressive disease characterised by cartilage degradation,
subchondral bone remodelling and inflammation of the synovium. The disease is associated …

MRI-visible mesoporous polydopamine nanoparticles with enhanced antioxidant capacity for osteoarthritis therapy

S Liu, C Zhang, Y Zhou, F Zhang, X Duan, Y Liu… - Biomaterials, 2023 - Elsevier
Since the progression of osteoarthritis (OA) is closely associated with synovitis and cartilage
destruction, the inhibition of inflammatory responses in synovial macrophages and reactive …

[HTML][HTML] Antimicrobial peptides could antagonize uncontrolled inflammation via Toll-like 4 receptor

DF Buccini, BC Roriz, JM Rodrigues… - … in Bioengineering and …, 2022 - frontiersin.org
Antimicrobial peptides are part of the organism's defense system. They are multifunctional
molecules capable of modulating the host's immune system and recognizing molecules …

Healthy and osteoarthritis-affected joints facing the cellular crosstalk

S Semenistaja, S Skuja, A Kadisa, V Groma - International Journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic, progressive, severely debilitating, and multifactorial joint
disease that is recognized as the most common type of arthritis. During the last decade, it …

Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor

P Steinwerth, J Bertrand, V Sandt, S Marchal, J Sahana… - Biomolecules, 2023 - mdpi.com
Over the last 30 years, the prevalence of osteoarthritis (OA), a disease characterized by a
loss of articular cartilage, has more than doubled worldwide. Patients suffer from pain and …

Type I IFN in Glomerular Disease: Scarring beyond the STING

AP Jimenez-Uribe, S Mangos, E Hahm - International Journal of …, 2024 - mdpi.com
The field of nephrology has recently directed a considerable amount of attention towards the
stimulator of interferon genes (STING) molecule since it appears to be a potent driver of …

[HTML][HTML] Causal associations between common musculoskeletal disorders and dementia: a Mendelian randomization study

J Wang, M Yang, Y Tian, R Feng, K Xu… - Frontiers in Aging …, 2023 - ncbi.nlm.nih.gov
Methods Two-sample Mendelian randomization (MR) was used in this study. MR analysis
based on gene-wide association study (GWAS) data on osteoarthritis (OA), dementia with …

Attenuative effects of collagen peptide from milkfish (Chanos chanos) scales on ovariectomy‐induced osteoporosis

JJ Chuu, JW Lu, HJ Chang, YH Chu… - Food Science & …, 2024 - Wiley Online Library
Osteoporosis is characterized by low bone mass, bone microarchitecture disruption, and
collagen loss, leading to increased fracture risk. In the current study, collagen peptides were …

The immunological facets of chondrocytes in osteoarthritis: A narrative review

P Sengprasert, O Kamenkit, A Tanavalee… - The Journal of …, 2024 - jrheum.org
Osteoarthritis (OA) is a disease in which the pathogenesis affects the joint and its
surrounding tissues. Cartilage degeneration is the main hallmark of OA, and chondrocytes …