Addressing phenoconversion: the Achilles' heel of personalized medicine
RR Shah, RL Smith - British journal of clinical pharmacology, 2015 - Wiley Online Library
Phenoconversion is a phenomenon that converts genotypic extensive metabolizers (EM s)
into phenotypic poor metabolizers (PM s) of drugs, thereby modifying their clinical response …
into phenotypic poor metabolizers (PM s) of drugs, thereby modifying their clinical response …
CYP450 genotype and pharmacogenetic association studies: a critical appraisal
RR Shah, A Gaedigk, A LLerena… - …, 2016 - Future Medicine
Despite strong pharmacological support, association studies using genotype-predicted
phenotype as a variable have yielded conflicting or inconclusive evidence to promote …
phenotype as a variable have yielded conflicting or inconclusive evidence to promote …
Confirmatory testing prior to initiating onychomycosis therapy is cost-effective
AK Gupta, SG Versteeg… - Journal of Cutaneous …, 2018 - journals.sagepub.com
Background: Onychomycosis can be investigated by sampling. Information gleaned includes
nail bed involvement, nail plate penetration, fungal viability, and species identification …
nail bed involvement, nail plate penetration, fungal viability, and species identification …
Common drug-drug interactions in antifungal treatments for superficial fungal infections
AK Gupta, SG Versteeg, NH Shear - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Antifungal agents can be co-administered alongside several other medications
for a variety of reasons such as the presence of comorbidities. Pharmacodynamic …
for a variety of reasons such as the presence of comorbidities. Pharmacodynamic …
Can perhexiline be utilized without long-term toxicity? A clinical practice audit
Background: Perhexiline, originally used as a first-line prophylactic antianginal agent, is now
regarded primarily as a treatment for otherwise refractory myocardial ischemia. Recent …
regarded primarily as a treatment for otherwise refractory myocardial ischemia. Recent …
Antifungal drugs
DS McManus - Side Effects of Drugs Annual, 2015 - Elsevier
Abstract The Side Effects of Drugs Annuals is a series of volumes in which the adverse
effects of drugs and adverse reactions to them are surveyed. The series supplements the …
effects of drugs and adverse reactions to them are surveyed. The series supplements the …
[HTML][HTML] Analysis of the mechanism of prolonged persistence of drug interaction between terbinafine and amitriptyline or nortriptyline
A Mikami, S Hori, H Ohtani, Y Sawada - … and Pharmaceutical Bulletin, 2017 - jstage.jst.go.jp
The purpose of the study was to quantitatively estimate and predict drug interactions
between terbinafine and tricyclic antidepressants (TCAs), amitriptyline or nortriptyline, based …
between terbinafine and tricyclic antidepressants (TCAs), amitriptyline or nortriptyline, based …
Antifungal drugs
DS McManus - Side Effects of Drugs Annual, 2016 - Elsevier
Abstract The Side Effects of Drugs Annuals is a series of volumes in which the adverse
effects of drugs and adverse reactions to them are surveyed. The series supplements the …
effects of drugs and adverse reactions to them are surveyed. The series supplements the …
Prospecção de sais imidazólicos com potencial antifúngico contra dermatófitos multirresistentes: estudo das relações de estrutura-atividade, dos mecanismos de …
DF Dalla Lana - 2015 - lume.ufrgs.br
As dermatofitoses são infecções cutâneas, causadas por fungos filamentosos
dermatofíticos, cuja incidência tem aumentado cada vez mais. Assim, este trabalho teve …
dermatofíticos, cuja incidência tem aumentado cada vez mais. Assim, este trabalho teve …