Hypertension (HTN) is a major modifiable risk factor for cardiovascular disease (CVD)
morbidity and mortality. The left ventricle (LV) is a primary target for HTN end-organ damage …

Safflower (Carthamus tinctorius L.) is cultivated in various countries for the flavonoid
compounds it contains. These flavonoids have been used in many industries as drugs …

Hypertension-mediated pathological cardiac remodeling often progresses to heart failure.
Elabela, mainly expressed in the cardiac microvascular endothelial cells (CMVECs) …

Abstract Sodium-glucose cotransporter 2 (SGLT2) inhibitors have evident cardiovascular
benefits in patients with type 2 diabetes with or at high risk for atherosclerotic cardiovascular …

Primary aldosteronism (PA) is a common cause of secondary hypertension and is
associated with worse cardiovascular outcomes. The elevated aldosterone in PA leads to …

Myocardial interstitial fibrosis (MIF) is a histological hallmark of several cardiac diseases that
alter myocardial architecture and function and are associated with progression to heart …

Background Although genotyping allows family screening and influences risk-stratification in
patients with nonischemic dilated cardiomyopathy (DCM) or isolated left ventricular systolic …

Hypertensive heart disease (HHD) is currently the second leading cause of heart failure. The
prevalence of HHD and its associated risk of heart failure have increased despite substantial …

Aims The heart undergoes pathological remodelling under increased stress and neuronal
imbalance. MicroRNAs (miRNAs) are involved in post-transcriptional regulation of genes in …

Hypertensive heart disease (HHD) can no longer be considered as the beneficial adaptive
result of the hypertrophy of cardiomyocytes in response to pressure overload leading to the …