[HTML][HTML] Novel therapeutic approaches to liver fibrosis based on targeting oxidative stress
A Blas-García, N Apostolova - Antioxidants, 2023 - mdpi.com
Chronic liver disease (CLD) constitutes a growing global health issue, with no effective
treatments currently available. Oxidative stress closely interacts with other cellular and …
treatments currently available. Oxidative stress closely interacts with other cellular and …
[HTML][HTML] Redox biology and liver fibrosis
F Bellanti, D Mangieri, G Vendemiale - International Journal of Molecular …, 2023 - mdpi.com
Hepatic fibrosis is a complex process that develops in chronic liver diseases. Even though
the initiation and progression of fibrosis rely on the underlying etiology, mutual mechanisms …
the initiation and progression of fibrosis rely on the underlying etiology, mutual mechanisms …
[HTML][HTML] Oxidatively stressed extracellular microenvironment drives fibroblast activation and kidney fibrosis
L Li, M Lu, Y Peng, J Huang, X Tang, J Chen, J Li… - Redox Biology, 2023 - Elsevier
Kidney fibrosis is associated with tubular injury, oxidative stress and activation of interstitial
fibroblasts. However, whether these events are somehow connected is poorly understood. In …
fibroblasts. However, whether these events are somehow connected is poorly understood. In …
An update on current and emerging drug treatments for idiopathic pulmonary fibrosis
A Trachalaki, N Sultana, AU Wells - Expert Opinion on …, 2023 - Taylor & Francis
ABSTRACT Introduction Idiopathic Pulmonary Fibrosis (IPF) is a progressive and
devastating lung disease, characterized by progressive lung scarring. Areas covered Prior to …
devastating lung disease, characterized by progressive lung scarring. Areas covered Prior to …
[HTML][HTML] Setanaxib mitigates oxidative damage following retinal ischemia-reperfusion via NOX1 and NOX4 inhibition in retinal ganglion cells
J Liao, Z Lai, G Huang, J Lin, W Huang, Y Qin… - Biomedicine & …, 2024 - Elsevier
Glaucoma, a prevalent cause of permanent visual impairment worldwide, is characterized by
the progressive degeneration of retinal ganglion cells (RGCs). NADPH oxidase (NOX) 1 and …
the progressive degeneration of retinal ganglion cells (RGCs). NADPH oxidase (NOX) 1 and …
The selective NOX4 inhibitor GLX7013159 decreases blood glucose concentrations and human beta-cell apoptotic rates in diabetic NMRI nu/nu mice transplanted …
Abstract NADPH oxidase 4 (NOX4) inhibition has been reported to mitigate diabetes-
induced beta-cell dysfunction and improve survival in vitro, as well as counteract high-fat …
induced beta-cell dysfunction and improve survival in vitro, as well as counteract high-fat …
[HTML][HTML] Cytochrome-Derived EETs, VEGF-A, and NOX4: Piecing the Puzzle Together
K Jandeleit-Dahm, J Meister - Diabetes, 2023 - Am Diabetes Assoc
In this issue of Diabetes, Njeim et al.(1) describe, for the first time, vascular endothelial
growth factor A (VEGF-A) as a link between reduced cytochrome P450 isoform–derived …
growth factor A (VEGF-A) as a link between reduced cytochrome P450 isoform–derived …
[PDF][PDF] Novel Therapeutic Approaches to Liver Fibrosis Based on Targeting Oxidative Stress. Antioxidants 2023, 12, 1567
A Blas-García, N Apostolova - 2023 - academia.edu
Chronic liver disease (CLD) constitutes a growing global health issue, with no effective
treatments currently available. Oxidative stress closely interacts with other cellular and …
treatments currently available. Oxidative stress closely interacts with other cellular and …