Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

National space agencies and private corporations aim at an extended presence of humans
in space in the medium to long term. Together with currently suboptimal technology …

To establish the accuracy of transcranial Doppler ultrasound (TCD) measures of middle
cerebral artery (MCA) cerebral blood flow velocity (CBFV) as a surrogate of cerebral blood …

Obstructive sleep apnea (OSA) is highly prevalent but very frequently undiagnosed. OSA is
an independent risk factor for depression and cognitive impairment/dementia. Herein the …

Background Changes in the cerebral hemispheric white matter, detectable with increasing
frequency by modern neuroimaging methods, are associated with aging and conceivably …

Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …

It is known that cerebral blood flow declines with age in sedentary adults, although previous
studies have involved small sample sizes, making the exact estimate of decline imprecise …

Background and aim COVID-19 pandemic has resulted in an unprecedented increased
usage of Personal protective equipment (PPE) by healthcare-workers. PPE usage causes …

Nitric oxide (NO) is undoubtedly quite an important intercellular messenger in cerebral and
peripheral hemodynamics. This molecule, formed by constitutive isomers of NO synthase …

It is increasingly recognized that obesity is a risk factor for microvascular disease, involving
both structural and functional changes in the microvasculature. This review aims to describe …