Biomarker development, improvement, and clinical implementation in the context of kidney
disease have been a central focus of biomedical research for decades. To this point, only …

Apoptosis of endothelial cells prompts the release of apoptotic exosome-like vesicles
(ApoExos), subtype extracellular vesicles secreted by apoptotic cells after caspase-3 …

Serum or plasma is frequently utilized in biomedical research; however, its application is
impeded by the requirement for invasive sample collection. The non-invasive nature of urine …

Background: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) play key roles in
diabetic kidney disease (DKD). The miR-379 megacluster of miRNAs and its host transcript …

ABSTRACT Matrix metalloproteinase 7 (MMP-7) is a secreted endopeptidase involved in the
degradation of extracellular matrix components and the activation of cytokines and growth …

Given the pathophysiological continuum of chronic kidney disease (CKD), different
molecular determinants affecting progression may be associated with distinct disease …

Background. Renal-hepatic dysfunction, which often occurs in liver dysfunction, requires the
use of effective and safe nephroprotective agents. Human placenta hydrolysates (HPH) are …

Сhronic kidney Disease (CKD) is the cause of both morbidity and mortality worldwide. In
Ukraine, 12% of the population is diagnosed with CKD. Significantly worsen the quality of …

Background Autosomal dominant polycystic kidney disease (ADPKD) is one of the most
prevalent monogenic human diseases. It is mostly caused by pathogenic variants in PKD1 …

Introduction Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as novel
therapeutics to treat diabetic kidney disease (DKD). Although the beneficial effects of …