Update on current and new potential immunotherapies in breast cancer, from bench to bedside

E Alaluf, MM Shalamov, A Sonnenblick - Frontiers in immunology, 2024 - frontiersin.org
Impressive advances have been seen in cancer immunotherapy during the last years.
Although breast cancer (BC) has been long considered as non-immunogenic …

Prognostic role of macrophages and mast cells in the microenvironment of hepatocellular carcinoma after resection

E Ali, L Červenková, R Pálek, F Ambrozkiewicz… - BMC cancer, 2024 - Springer
Background The prognostic significance of mast cells and different phenotypes of
macrophages in the microenvironment of hepatocellular carcinoma (HCC) following …

The Gastric Cancer Immune Prognostic Score (GCIPS) Shows Potential in Predicting an Unfavorable Prognosis for Gastric Cancer Patients Undergoing Immune …

Y Zuo, H Sun, H Pan, R Zhao, Y Xue, H Song - Biomedicines, 2024 - mdpi.com
Simple Summary In the current landscape of gastric cancer treatment, identifying patients
who can benefit from immunotherapy and determining high-risk individuals post …

Discrepant Phenotyping of Monocytes Based on CX3CR1 and CCR2 Using Fluorescent Reporters and Antibodies

K Sommer, H Garibagaoglu, EM Paap, M Wiendl… - Cells, 2024 - mdpi.com
Monocytes, as well as downstream macrophages and dendritic cells, are essential players
in the immune system, fulfilling key roles in homeostasis as well as in inflammatory …

Comprehensive analysis of human monocyte subsets using full-spectrum flow cytometry and hierarchical marker clustering

C Li, M Xiao, S Geng, Y Wang, L Zeng, P Lai… - Frontiers in …, 2024 - frontiersin.org
Introduction Exploring monocytes' roles within the tumor microenvironment is crucial for
crafting targeted cancer treatments. Methods This study unveils a novel methodology …

Dendrobium officinale polysaccharide Converts M2 into M1 Subtype Macrophage Polarization via the STAT6/PPAR-r and JAGGED1/NOTCH1 Signaling Pathways to …

Y Zhao, X Lu, H Huang, Y Yao, H Liu, Y Sun - Molecules, 2023 - mdpi.com
Dendrobium officinale polysaccharide (DOP) has shown various biological activities.
However, the ability of DOP to participate in immune regulation during anti-gastric cancer …

EBV Impact in Peripheral Macrophages' Polarization Cytokines in Pediatric Patients

A Moyano, N Ferressini Gerpe, ME Amarillo… - Viruses, 2023 - mdpi.com
Macrophages are exceptionally flexible cells. The presence of inflammatory cytokines such
as IFN-γ and TNF-α results in an M1 (CD68) activation, while cytokines such as IL-10 or TGF …

Inflammatory status predicts prognosis in patients with gastric cancer with early pyloric stenosis who underwent radical resection: A propensity score‑matching …

L He, J Li, X Li, X Wang, Q Yan - Oncology Letters, 2024 - spandidos-publications.com
The inflammatory status of patients is closely related to their nutritional status, and the impact
of inflammatory status on patients with pyloric stenosis remains unclear. The present study …

Novel IL4I1 inhibitors for treating cancer

RW Sabnis - ACS Medicinal Chemistry Letters, 2023 - ACS Publications
Novel IL4I1 Inhibitors for Treating Cancer Page 1 Novel IL4I1 Inhibitors for Treating Cancer
Ram W. Sabnis* Cite This: ACS Med. Chem. Lett. 2023, 14, 700−701 Read Online ACCESS …

Overexpression of SerpinB9 in non-seminomatous germ cell tumors

T Anami, Y Ibe, L Li, Y Komohara, H Hirao… - Medical Molecular …, 2024 - Springer
Serpinb9 is an inhibitor of granzyme B and is potentially involved in the immune escape of
tumor cells. In the present study, bioinformatics analysis using open databases suggested …