[PDF][PDF] BDNF signaling in context: From synaptic regulation to psychiatric disorders
Brain-derived neurotrophic factor (BDNF) is a neuropeptide that plays numerous important
roles in synaptic development and plasticity. While its importance in fundamental physiology …
roles in synaptic development and plasticity. While its importance in fundamental physiology …
Neurotrophic factor BDNF, physiological functions and therapeutic potential in depression, neurodegeneration and brain cancer
Brain-derived neurotrophic factor (BDNF) is one of the most distributed and extensively
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …
studied neurotrophins in the mammalian brain. BDNF signals through the tropomycin …
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
R Moliner, M Girych, CA Brunello, V Kovaleva… - Nature …, 2023 - nature.com
Psychedelics produce fast and persistent antidepressant effects and induce neuroplasticity
resembling the effects of clinically approved antidepressants. We recently reported that …
resembling the effects of clinically approved antidepressants. We recently reported that …
[HTML][HTML] Brain-derived neurotrophic factor signaling in depression and antidepressant action
E Castrén, LM Monteggia - Biological psychiatry, 2021 - Elsevier
Neurotrophic factors, particularly BDNF (brain-derived neurotrophic factor), have been
associated with depression and antidepressant drug action. A variety of preclinical and …
associated with depression and antidepressant drug action. A variety of preclinical and …
[HTML][HTML] The role of BDNF on neural plasticity in depression
T Yang, Z Nie, H Shu, Y Kuang, X Chen… - Frontiers in cellular …, 2020 - frontiersin.org
Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …
depression is closely related to the abnormal neural plasticity processes occurring in the …
[PDF][PDF] Antidepressant drugs act by directly binding to TRKB neurotrophin receptors
It is unclear how binding of antidepressant drugs to their targets gives rise to the clinical
antidepressant effect. We discovered that the transmembrane domain of tyrosine kinase …
antidepressant effect. We discovered that the transmembrane domain of tyrosine kinase …
Deep learning-based predictive identification of neural stem cell differentiation
The differentiation of neural stem cells (NSCs) into neurons is proposed to be critical in
devising potential cell-based therapeutic strategies for central nervous system (CNS) …
devising potential cell-based therapeutic strategies for central nervous system (CNS) …
Brain-derived neurotrophic factor in brain disorders: focus on neuroinflammation
B Lima Giacobbo, J Doorduin, HC Klein… - Molecular …, 2019 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
healthy and diseased brain. As a result, there is a large body of evidence that associates …
healthy and diseased brain. As a result, there is a large body of evidence that associates …
Gut–brain axis: role of gut microbiota on neurological disorders and how probiotics/prebiotics beneficially modulate microbial and immune pathways to improve brain …
K Suganya, BS Koo - International journal of molecular sciences, 2020 - mdpi.com
The gut microbiome acts as an integral part of the gastrointestinal tract (GIT) that has the
largest and vulnerable surface with desirable features to observe foods, nutrients, and …
largest and vulnerable surface with desirable features to observe foods, nutrients, and …
BDNF: a key factor with multipotent impact on brain signaling and synaptic plasticity
P Kowiański, G Lietzau, E Czuba, M Waśkow… - Cellular and molecular …, 2018 - Springer
Brain-derived neurotrophic factor (BDNF) is one of the most widely distributed and
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …
extensively studied neurotrophins in the mammalian brain. Among its prominent functions …