The brain derived neurotrophic factor (BDNF) is a crucial neuromodulator in pain
transmission both in peripheral and central nervous system (CNS). Despite evidence of a …

We report the construction of artificial cells that chemically communicate with mammalian
cells under physiological conditions. The artificial cells respond to the presence of a small …

As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Brain-derived neurotrophic factor (BDNF) is a member of a family of neurotrophins which
include nerve growth factor, neurotrophin 3, and neurotrophin 4. Studies over the last three …

From animal research, it is known that combining physical activity with sensory enrichment
has stronger and longer-lasting effects on the brain than either treatment alone. For humans …

Stem cell therapies have shown promise in promoting recovery in stroke but have been
limited by poor cell survival and differentiation. We have developed a hyaluronic acid (HA) …

Background Pyrethroid metabolites are widely detectable in urine from the general
population, including pregnant women and children. Pyrethroids are neurotoxic and …

Opioid receptors are widely distributed throughout the brain and play an essential role in
modulating aspects of human mood, reward, and well-being. Accumulating evidence …

Major depressive disorder (MDD) is a debilitating neuropsychological disorder, which has
caused serious health and socio-economic burdens worldwide. A growing body of evidence …

Neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and
Huntington's disease currently affect tens of millions of people worldwide. Unfortunately, as …