Potential role of natural antioxidant products in oncological diseases

P Marino, G Pepe, MG Basilicata, V Vestuto… - Antioxidants, 2023 - mdpi.com
Nutrition has a significant effect and a crucial role in disease prevention. Low consumption
of fruit and vegetables and a sedentary lifestyle are closely related with the onset and …

Drug design strategies that aim to improve the low solubility and poor bioavailability conundrum in quercetin derivatives

SR Alizadeh, N Savadkouhi… - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Scientists are especially interested in polyphenols, particularly flavonoids.
Quercetin, a flavonoid, has demonstrated various therapeutic properties, such as …

Investigation of Cardioprotective Activity of Silybin: Network Pharmacology, Molecular Docking, and In Vivo Studies

P Kumar Pasala, M Donakonda, PS Dintakurthi… - …, 2023 - Wiley Online Library
The abundant health benefits of silybin are known to benefit people with myocardial
infarction (MI). However, their mechanisms of action are not precise. To address this …

A signaling crosstalk links SNAIL to the 37/67 kDa laminin-1 receptor ribosomal protein SA and regulates the acquisition of a cancer stem cell molecular signature in …

L Gresseau, ME Roy, S Duhamel, B Annabi - Cancers, 2022 - mdpi.com
Simple Summary In vivo studies have shown that 3D neurosphere formation is a significant
predictor of clinical outcome in glioma patients, and is a robust, independent predictor of …

Anti-inflammatory and antioxidative effects of dexpanthenol on nicotine-induced lung injury in rats

M Aslan, E Gürel, N Üremiş, MM Üremiş… - Toxicology and …, 2023 - Springer
Aim Lung inflammation is a consequence of smoking, tobacco use, nicotine addiction, and
the accumulation of toxicants in the body. This study aimed to investigate the association …

Dietary Polyphenols: Review on Chemistry/Sources, Bioavailability/Metabolism, Antioxidant Effects, and Their Role in Disease Management

M Rudrapal, G Rakshit, RP Singh, S Garse, J Khan… - Antioxidants, 2024 - mdpi.com
Polyphenols, as secondary metabolites ubiquitous in plant sources, have emerged as
pivotal bioactive compounds with far-reaching implications for human health. Plant …

Dietary Intake of (Poly) phenols and Risk of All-Cause and Cause-Specific Mortality in the Mexican Teachers' Cohort Study

J Castañeda, E Almanza-Aguilera, A Monge… - The Journal of …, 2024 - Elsevier
Background Observational studies have reported that total (poly) phenol intake is associated
with a reduction in all-cause and cardiovascular mortality, but mainly from high-income …

Plant-based therapeutics for chronic obstructive pulmonary diseases: Nanoformulation strategies to overcome delivery challenges

S Kokkinis, M Singh, KR Paudel, G De Rubis, AB Saeid… - Food Bioscience, 2024 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a widespread global health problem
marked by increasing airflow limitation and chronic airway inflammation. Conventional …

[HTML][HTML] Protective effect of apple polyphenols on H2O2-induced oxidative stress damage in human colon adenocarcinoma Caco-2 cells

T Miao, G Song, J Yang - Chemical and Pharmaceutical Bulletin, 2023 - jstage.jst.go.jp
Apple is an important dietary agent for human and apple polyphenols (AP) are the main
secondary metabolites of apples. In this study, the protective effects of AP on hydrogen …

Epigallocatechin Gallate Ameliorates Nicotine Withdrawal Conditions‐Induced Somatic and Affective Behavior Changes in Mice and Its Molecular Mechanism

M Rahmadi, AD Nurhan, RIA Rahmawati… - Behavioural …, 2023 - Wiley Online Library
In nicotine withdrawal (NW) conditions, molecular changes, such as increasing corticotropin‐
releasing factor (CRF) in the amygdala, and melanocortin signaling in the hypothalamus …