Mitochondria are believed to have originated through an ancient endosymbiotic process in
which proteobacteria were captured and co-opted for energy production and cellular …

Intercellular signaling and component conduction are essential for multicellular organisms'
homeostasis, and mitochondrial transcellular transport is a key example of such cellular …

The recovery of mitochondrial quality control (MQC) may bring innovative solutions for
neuroprotection, while imposing a significant challenge given the need of holistic …

Mitochondrial dysfunction is a central event in the pathogenesis of several degenerative
brain disorders. It entails fission and fusion dynamics disruption, progressive decline in …

Müller glial cells (MC) support various metabolic functions of the retinal neurons, and
maintain the homeostasis. Oxidative stress is intensified with aging, and in human retina …

To clarify our understanding of glial phagocytosis in retinal development, we used real-time
imaging of larval zebrafish to provide cell-type specific resolution of this process. We show …

Mammalian cells release a wealth of materials to their surroundings. Emerging data suggest
these materials can even be mitochondria with perturbed morphology and aberrant function …

Mitochondria are metabolic and signalling hubs that integrate a plethora of interconnected
processes to maintain cell homeostasis. They are also dormant mediators of inflammation …

The retina is part of the central nervous system specialized for vision. Inherited retinal
diseases (IRD) are a group of clinically and genetically heterogenous disorders that lead to …

Intercellular communication is pivotal in mediating the transfer of mitochondria from donor to
recipient cells. This process orchestrates various biological functions, including tissue repair …