The airway epithelium protects us from environmental insults, which we encounter with
every breath. Not only does it passively filter large particles, it also senses potential danger …

Respiratory fungal infection is a severe clinical problem, especially in patients with
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …

Chronic lung disease determines the morbidity and mortality of cystic fibrosis (CF) patients.
The pulmonary immune response in CF is characterized by an early and non-resolving …

Aspergillus fumigatus is an environmental filamentous fungus that also acts as an
opportunistic pathogen able to cause a variety of symptoms, from an allergic response to a …

Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Aspergillus fumigatus is an ubiquitous, saprophytic mould that forms and releases airborne
conidia which are inhaled by humans on a daily basis. When the immune system is …

Hundred-thousands of fungal species are present in our environment, including normal
colonizers that constitute part of the human microbiota. The homeostasis of host-fungus …

Knowledge of fungal pathogenesis and host immune response can help to optimize the
management of fungal infections. Greater understanding of these processes may aid …

Respiratory epithelia fulfil multiple roles beyond that of gaseous exchange, also acting as
primary custodians of lung sterility and inflammatory homeostasis. Inhaled fungal spores …

The interplay between Aspergillus fumigatus and the host immune response in lung
infection has been subject of studies over the last years due to its importance in …