[HTML][HTML] Updated epidemiology of gastric cancer in Asia: Decreased incidence but still a big challenge

WS Shin, F Xie, B Chen, P Yu, J Yu, KF To, W Kang - Cancers, 2023 - mdpi.com
Simple Summary Gastric cancer (GC) is regarded as one of the most perilous malignancies
globally, with over one billion new cases and seven hundred and eighty-three thousand …

Rationalizing the therapeutic potential of apigenin against cancer

SA Ahmed, D Parama, E Daimari, S Girisa, K Banik… - Life Sciences, 2021 - Elsevier
Background Despite the remarkable advances made in the diagnosis and treatment of
cancer during the past couple of decades, it remains the second largest cause of mortality in …

[HTML][HTML] P38 kinase in gastrointestinal cancers

T Phan, XH Zhang, S Rosen, LG Melstrom - Cancer Gene Therapy, 2023 - nature.com
Gastrointestinal cancers are a leading cause of cancer morbidity and mortality worldwide
with 4.2 million new cases and 3.2 million deaths estimated in 2020. Despite the advances …

[HTML][HTML] Long non-coding RNAs (lncRNAs) as regulators of the PI3K/AKT/mTOR pathway in gastric carcinoma

I Riquelme, P Pérez-Moreno, B Mora-Lagos… - International journal of …, 2023 - mdpi.com
Gastric cancer (GC) represents~ 10% of the global cancer-related deaths, increasingly
affecting the younger population in active stages of life. The high mortality of GC is due to …

Exosomal circRNAs in cancer: implications for therapy resistance and biomarkers

Z Lin, Y Ji, J Zhou, G Li, Y Wu, W Liu, Z Li, T Liu - Cancer Letters, 2023 - Elsevier
Despite the advances in cancer treatment in recent years, the development of resistance to
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …

[HTML][HTML] RBMS1 promotes gastric cancer metastasis through autocrine IL-6/JAK2/STAT3 signaling

M Liu, H Li, H Zhang, H Zhou, T Jiao, M Feng… - Cell Death & …, 2022 - nature.com
Metastasis is the most important reason for the poor prognosis of gastric cancer (GC)
patients, and the mechanism urgently needs to be clarified. Here, we explored a prognostic …

[HTML][HTML] A novel necroptosis-related gene index for predicting prognosis and a cold tumor immune microenvironment in stomach adenocarcinoma

M Khan, J Lin, B Wang, C Chen, Z Huang… - Frontiers in …, 2022 - frontiersin.org
Background Gastric cancer (GC) represents a major global clinical problem with very limited
therapeutic options and poor prognosis. Necroptosis, a recently discovered inflammatory …

Detailed curriculum vitae of HER2-targeted therapy

XN Zhang, Y Gao, XY Zhang, NJ Guo, WQ Hou… - Pharmacology & …, 2023 - Elsevier
With the booming development of precision medicine, molecular targeted therapy has been
widely used in clinical oncology treatment due to a smaller number of side effects and its …

[HTML][HTML] The burden and trend of gastric cancer and possible risk factors in five Asian countries from 1990 to 2019

FL Ning, J Lyu, JP Pei, WJ Gu, NN Zhang, SY Cao… - Scientific Reports, 2022 - nature.com
The burdens and trends of gastric cancer are poorly understood, especially in high-
prevalence countries. Based on the Global Burden of Disease Study 2019, we analyzed the …

H19 promotes aerobic glycolysis, proliferation, and immune escape of gastric cancer cells through the microRNA‐519d‐3p/lactate dehydrogenase a axis

L Sun, J Li, W Yan, Z Yao, R Wang, X Zhou… - Cancer …, 2021 - Wiley Online Library
Long noncoding RNAs (lncRNAs) have been investigated in multiple human cancers
including gastric cancer (GC). Our research aims to explore the role of H19 in aerobic …