The organic arsenical-derived thioredoxin and glutathione system inhibitor ACZ2 induces apoptosis and autophagy in gastric cancer via ROS-dependent ER stress

Y Li, W She, T Guo, T Huang, P Liu, X Xu… - Biochemical …, 2023 - Elsevier
Developing novel drugs for gastric cancer (GC) is greatly needed, and a reactive oxygen
species (ROS)-modulating strategy has been demonstrated to be useful for cancer …

The prognostic marker elastin correlates with epithelial–mesenchymal transition and vimentin‐positive fibroblasts in gastric cancer

T Fang, L Zhang, X Yin, Y Wang… - The Journal of …, 2023 - Wiley Online Library
Elastin (ELN) fibers are essential constituents of the tumor microenvironment of gastric
cancer (GC). However, few studies have investigated the clinical prognostic significance of …

Non-coding RNAs in gastric cancer: from malignant hallmarks to clinical applications

D Chen, S Ping, Y Xu, M Wang, X Jiang… - Frontiers in Cell and …, 2021 - frontiersin.org
Gastric cancer (GC) is one of the most lethal malignancies worldwide. However, the
molecular mechanisms underlying gastric carcinogenesis remain largely unknown. Over the …

Interaction of ncRNA and epigenetic modifications in gastric cancer: focus on histone modification

Q Yang, Y Chen, R Guo, Y Dai, L Tang, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
Gastric cancer has developed as a very common gastrointestinal tumors, with recent
effective advancements in the diagnosis and treatment of early gastric cancer. However, the …

Risk factors of lymph node metastasis and its prognostic significance in early gastric cancer: a multicenter study

J Wang, L Wang, S Li, F Bai, H Xie, H Shan… - Frontiers in …, 2021 - frontiersin.org
Background Early gastric cancer (EGC) is invasive gastric cancer that invades no deeper
than the submucosa, regardless of lymph node metastasis (LNM). It is mainly treated by …

The macrophage-associated prognostic gene ANXA5 promotes immunotherapy resistance in gastric cancer through angiogenesis

Z Hong, P Wen, K Wang, X Wei, W Xie, S Rao, X Chen… - BMC cancer, 2024 - Springer
Gastric cancer (GC) remains a predominant form of malignant tumor globally, necessitating
innovative non-surgical therapeutic approaches. This investigation aimed to delineate the …

[PDF][PDF] MATTERHORN: Efficacy and safety of neoadjuvant-adjuvant durvalumab and FLOT chemotherapy in resectable gastric and gastroesophageal junction cancer …

YY Janjigian, E Van Cutsem, K Muro… - J Clin …, 2021 - postersessiononline.eu
MATTERHORN study design: Patients diagnosed with histologically confirmed, Stage II or
higher, resectable GC/GEJC not previously Page 1 wcgic2021 Presented at …

[HTML][HTML] Role of radiomics in the diagnosis and treatment of gastrointestinal cancer

Q Mao, MT Zhou, ZP Zhao, N Liu, L Yang… - World journal of …, 2022 - ncbi.nlm.nih.gov
Gastrointestinal cancer (GIC) has high morbidity and mortality as one of the main causes of
cancer death. Preoperative risk stratification is critical to guide patient management, but …

Solanum nigrum Linn.: Advances in anti-cancer activity and mechanism in digestive system tumors

H Pei, J Yang, W Li, X Luo, Y Xu, X Sun, Q Chen… - Medical Oncology, 2023 - Springer
Cancer has currently become a serious public health issue in many countries worldwide,
and tumors of the digestive system have attracted an increasing number of researchers' due …

Hsa-miR-34a-5p reverses multidrug resistance in gastric cancer cells by targeting the 3′-UTR of SIRT1 and inhibiting its expression

XJ Deng, HL Zheng, XQ Ke, M Deng, ZZ Ma, Y Zhu… - Cellular …, 2021 - Elsevier
Multidrug resistance (MDR) is a major obstacle to chemotherapy, which leads to ineffective
chemotherapy, an important treatment strategy for gastric cancer (GC). The abnormality of …