Clinical progress of anti-angiogenic targeted therapy and combination therapy for gastric cancer

D Xu, Y Luo, P Wang, J Li, L Ma, J Huang… - Frontiers in …, 2023 - frontiersin.org
The incidence of gastric cancer is increasing year by year. Most gastric cancers are already
in the advanced stage with poor prognosis when diagnosed, which means the current …

Efficacy and Safety of Brucea javanica Oil Emulsion Injection in the Treatment of Gastric Cancer: A Systematic Review and Meta-Analysis

X Wang, H Wang, L Cao, J Wu, T Lu, S Li, J Li - Frontiers in Nutrition, 2021 - frontiersin.org
Background: Gastric cancer (GC) is one of the most common digestive tract cancers and
ranks fifth in the incidence of malignant tumors worldwide. Brucea javanica oil emulsion …

Consumer perspectives on the adoption of a prehabilitation multimodal online program for patients undergoing cancer surgery

D Steffens, L Denehy, M Solomon, C Koh, N Ansari… - Cancers, 2023 - mdpi.com
Simple Summary This study explored the views of 30 gastrointestinal cancer patients on the
adoption of a prehabilitation multimodal program, including exercise, nutrition and …

Bioinformatics analyses for the identification of tumor antigens and immune subtypes of gastric adenocarcinoma

S Wei, Q Sun, J Chen, X Li, Z Hu - Frontiers in Genetics, 2022 - frontiersin.org
Background: Although mRNA vaccines have been effective against multiple cancers, their
efficacy against stomach adenocarcinoma (STAD) remains undefined. Immunotyping can …

DKK1 Promotes Epithelial–Mesenchymal Transition and Cisplatin Resistance in Gastric Cancer via Activation of the PI3K/AKT Pathway

J Li, Y Zhang, F Ye, P Qian, Z Qin, D Li, L Ye, L Feng - Cancers, 2023 - mdpi.com
Simple Summary Dickkopf-related protein 1 (DKK1) plays different roles in different cancers,
and its aberrant expression is associated with tumor progression and poor prognosis …

Impact of intratumoural CD96 expression on clinical outcome and therapeutic benefit in gastric cancer

C Xu, H Fang, Y Gu, K Yu, J Wang, C Lin… - Cancer …, 2022 - Wiley Online Library
CD96 was identified as a novel immune checkpoint. However, the role of CD96 in the gastric
cancer (GC) microenvironment remains fragmentary. This study aimed to probe the clinical …

[HTML][HTML] Ferroptosis regulates key signaling pathways in gastrointestinal tumors: Underlying mechanisms and therapeutic strategies

R Rabitha, S Shivani, Y Showket… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Ferroptosis is an emerging novel form of non-apoptotic, regulated cell death that is heavily
dependent on iron and characterized by rupture in plasma membrane. Ferroptosis is distinct …

KIRREL promotes the proliferation of gastric cancer cells and angiogenesis through the PI3K/AKT/mTOR pathway

T Wang, S Chen, Z Wang, S Li, X Fei… - Journal of Cellular …, 2024 - Wiley Online Library
Anti‐angiogenesis is a promising therapeutic strategy for delaying tumour progression that
offers, new hope for gastric cancer targeted therapy. The purpose of this study was to …

ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination

S Geng, W Peng, X Wang, X Hu, H Liang, J Hou… - Cell death & …, 2022 - nature.com
Abstract Ariadne homolog 2 (ARIH2) is a key member of the RING-between-RING (RBR) E3
ligase family, which is characterized by an RBR domain involved in the polyubiquitination …

Cellular senescence-related genes: predicting prognosis in gastric cancer

L Dai, X Wang, T Bai, J Liu, B Chen, W Yang - Frontiers in Genetics, 2022 - frontiersin.org
Our study aimed to explore the effect of cellular senescence and to find potential therapeutic
strategies for gastric cancer. Cellular senescence-related genes were acquired from the …